Sarah Hatsell

Regeneron (United States) — United States

Medicine · Health Sciences

25h-index2.7kcitations52works2.42yr avg
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Research Topics

Heterotopic Ossification and Related Conditions(11), Parathyroid Disorders and Treatments(10), Wnt/β-catenin signaling in development and cancer(10), Medical Imaging and Pathology Studies(9), Hemoglobinopathies and Related Disorders(6)

Publications52 total

High-throughput copper speciation with SEC-UV-ICPMS: Insights from Wilson's disease mouse models
Analytica Chimica Acta·2026Open Access
A TMPRSS6-inhibiting mAb improves disease in a β-thalassemia mouse model and reduces iron in healthy humans
JCI Insight·2025· 1 citedOpen Access
Abstract 4147280: Combined BMP9 and BMP10 inhibition elicits Hereditary Hemorrhagic Telangiectasia (HHT)-like phenotypes in susceptible mice
Circulation·2024
TMPRSS6 Inhibition Rapidly Reverses Liver Iron Overload and Prevents an Increase of Splenic Pro-Inflammatory Macrophages in a Mouse Model of Beta-Thalassemia
Blood·2024Open Access
676 - Dupilumab increases levels of bone growth biomarker irrespective of prior use of systemic corticosteroids in children with moderate-to-severe atopic dermatitis
British Journal of Dermatology·2024· 1 cited
Coordinate regulation of Activin and Bone Morphogenetic Protein signaling by a lysosomal trafficking switch
2024· 2 citedOpen Access
How Activin A Became a Therapeutic Target in Fibrodysplasia Ossificans Progressiva
Biomolecules·2024· 13 citedOpen Access
Single Ascending Doses of REGN7999, a Monoclonal Antibody Inhibitor of TMPRSS6, Increase Serum Hepcidin and Cause Deep, Sustained Reductions in Serum Iron in Healthy Human Volunteers
Blood·2023· 1 cited
Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis
Nature Genetics·2023· 23 citedOpen Access
S281: TMPRSS6 INHIBITION WITH A MONOCLONAL ANTIBODY IMPROVES RED BLOOD CELL HEALTH AND IRON OVERLOAD IN A MOUSE MODEL OF BETA-THALASSEMIA
HemaSphere·2023Open Access
P93 Dupilumab treatment in children with moderate-to-severe atopic dermatitis increases levels of bone mineralization biomarkers
British Journal of Dermatology·2023· 1 citedOpen Access
Antibodies to sclerostin or G-CSF receptor partially eliminate bone or marrow adipocyte loss, respectively, following vertical sleeve gastrectomy
Bone·2023· 3 citedOpen Access
340 Dupilumab treatment of children with moderate-to-severe atopic dermatitis increases bone alkaline phosphatase, a marker of bone mineralization
British Journal of Dermatology·2023
TMPRSS6 Inhibition with a Monoclonal Antibody Improves Red Blood Cell Health and Reduces Hepatic Iron Loading in Mouse Models of Iron Overload Diseases
Blood·2022· 2 cited
Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
Journal of Clinical Investigation·2022· 60 citedOpen Access
Exome sequencing of 300,000 individuals implicates target genes for osteoporosis
Bone Reports·2022Open Access
ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
2021· 1 citedOpen Access
Anti-GDF11Treatment of β-Thalassemia Intermedia Mice Does Not Improve Erythropoiesis
Blood·2020· 1 cited
Activin A does not drive post-traumatic heterotopic ossification
Bone·2020· 36 cited
Abstract 89: Identifying The Myeloid Subpopulation Responsible For Tissue Fibrosis Across Organ Systems Via Machine Learning Parameterization And Predictive Transcriptomics
Plastic & Reconstructive Surgery Global Open·2020Open Access
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Frequent Co-authors

Aris N. Economides(28), Vincent Idone(13), Pamela Cowin(11), Kalyan C. Nannuru(9), Lily Huang(8), Nanditha Das(8), Andrew Murphy(8), Lili Wang(6), Liqin Xie(6), Paul B. Yu(6), Deepa K. Murugesh(6), Gabriela G. Loots(6), Susannah Brydges(6), Heinrich E. Lob(6), Aimy Sebastian(5), Xialing Wen(4), Tracey Rowlands(4), Jiun Chiun Chang(4), Bernd Christiansen(4), Senem Aykul(4)