Soheila Najafzadeh

Yale Cancer Center — United States

Neuroscience · Life Sciences

17h-index1.7kcitations44works9.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(12), Medical Imaging Techniques and Applications(12), Receptor Mechanisms and Signaling(7), Neurotransmitter Receptor Influence on Behavior(6), Epilepsy research and treatment(5)

Publications44 total

First-in-Human Study of<sup>18</sup>F-SynVesT-2: An SV2A PET Imaging Probe with Fast Brain Kinetics and High Specific Binding
Journal of Nuclear Medicine·2024· 12 citedOpen Access
Clinical correlates of dopamine transporter availability in cross-sectional and longitudinal studies with [18F]FE-PE2I PET: independent validation with new insights
Brain Communications·2024· 6 citedOpen Access
Age, gender and body-mass-index relationships with in vivo CB1 receptor availability in healthy humans measured with [11C]OMAR PET
NeuroImage·2022· 13 citedOpen Access
First-in-human evaluation of 18F-BMS-986327 as a novel PET tracer to assess lysophosphatidic acid receptor 1 (LPA1) target engagement in the lung
2022
Systemic inflammation enhances stimulant-induced striatal dopamine elevation in tobacco smokers
Brain Behavior and Immunity·2022· 4 citedOpen Access
Nicotine Patch Alters Patterns of Cigarette Smoking-Induced Dopamine Release: Patterns Relate to Biomarkers Associated With Treatment Response
Nicotine & Tobacco Research·2022· 10 citedOpen Access
Imaging brain cortisol regulation in PTSD with a target for 11β-hydroxysteroid dehydrogenase type 1
Journal of Clinical Investigation·2021· 16 citedOpen Access
Recently Abstinent Smokers Exhibit Mood-Associated Dopamine Dysfunction in the Ventral Striatum Compared to Nonsmokers: A [11C]-(+)-PHNO PET Study
Nicotine & Tobacco Research·2021· 6 citedOpen Access
Evaluation of [18F]SynVesT-2 for imaging SV2A in the human brain: kinetics, test-retest reproducibility, and binding specificity
2021· 1 cited
Assessment of test-retest reproducibility of [18F]SynVesT-1, a novel radiotracer for PET imaging of synaptic vesicle glycoprotein 2A
European Journal of Nuclear Medicine and Molecular Imaging·2021· 55 cited
PET Imaging Estimates of Regional Acetylcholine Concentration Variation in Living Human Brain
Cerebral Cortex·2020· 8 citedOpen Access
The aging rhesus macaque as a potential model for Alzheimer's disease/dementia: An <i>in vivo</i> study of [<sup>11</sup>C]PIB, [<sup>11</sup>C]UCB‐j, [<sup>18</sup>F]MK‐6240 and working memory performance
Alzheimer s & Dementia·2020· 3 citedOpen Access
Association between cerebrospinal fluid biomarkers of neurodegeneration and PET measurements of synaptic density in Alzheimer’s disease
Alzheimer s & Dementia·2020· 2 citedOpen Access
Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder
Molecular Psychiatry·2020· 54 cited
First-in-Human study of [18F]SynVesT-2, a novel SV2A radioligand with fast kinetics and high specific binding signals
2020· 9 cited
Nicotine patch reduces striatal smoking-induced dopamine release compared to placebo patch
2020
Inverse changes in raphe and cortical 5‐HT<sub>1B</sub> receptor availability after acute tryptophan depletion in healthy human subjects
Synapse·2020· 21 citedOpen Access
PET Imaging of Pancreatic Dopamine D<sub>2</sub> and D<sub>3</sub> Receptor Density with <sup>11</sup>C-(+)-PHNO in Type 1 Diabetes
Journal of Nuclear Medicine·2019· 26 citedOpen Access
P2‐349: ASSOCIATION BETWEEN MGLUR5 AND SYNAPTIC DENSITY: A MULTI‐TRACER STUDY OF HEALTHY AGING AND ALZHEIMER'S DISEASE
Alzheimer s & Dementia·2019· 1 citedOpen Access
IC‐P‐140: ASSOCIATION BETWEEN MGLUR5 AND SYNAPTIC DENSITY: A MULTI‐TRACER STUDY IN HEALTHY AGING AND ALZHEIMER'S DISEASE
Alzheimer s & Dementia·2019· 1 citedOpen Access
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Frequent Co-authors

Richard E. Carson(39), Nabeel Nabulsi(35), Yiyun Huang(35), Jim Ropchan(32), Mika Naganawa(18), David Labaree(15), Shu-fei Lin(13), David Matuskey(13), Jean‐Dominique Gallezot(9), Ming-Kai Chen(8), Shannan Henry(8), Ming‐Qiang Zheng(8), Ansel T. Hillmer(8), Alexander Neumeister(7), Kelly Cosgrove(7), Michael Kapinos(7), Amy F.T. Arnsten(6), Evan D. Morris(6), Adam P. Mecca(5), Takuya Toyonaga(5)