Sivaprakash Ramalingam

Institute of Genomics and Integrative Biology — India

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index1.4kcitations65works1.72yr avg
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Research Topics

CRISPR and Genetic Engineering(29), Hemoglobinopathies and Related Disorders(12), Mosquito-borne diseases and control(9), Iron Metabolism and Disorders(7), Advanced biosensing and bioanalysis techniques(6)

Publications65 total

AI-guided CAR designs and targeted pathway modulation to enhance multi-antigen CAR T cell durability and overcome antigen escape
Nature Communications·2026Open Access
Decoding the multifaceted role of erythrocyte PMCA4b in oxidative stress-mediated malaria protection and artemisinin resistance
mBio·2025Open Access
Arsenic Induces Cytotoxicity in Pulmonary Epithelial Cells by Regulating the MicroRNA‐195‐5p/E2F7 Axis: The Impact of Tannic Acid From Natural Sources
Journal of Applied Toxicology·2025· 1 cited
Identification and Functional Validation of Novel Pathogenic Variants in Primary Immunodeficiencies
European Journal of Immunology·2025
CRISPR-mediated generation of a tumor-associated antigen-deficient Raji platform to investigate antigen loss in CAR-T cell therapy
Frontiers in Genome Editing·2025· 1 citedOpen Access
CRISPR/Cas9-mediated identification of human macrophage SphK1 as druggable target for development of anti-leishmanial chemotherapeutics
2025Open Access
AI-Guided CAR Designs and AKT3 Degradation Synergize to Enhance Bispecific and Trispecific CAR-T Cell Persistence and Overcome Antigen Escape
2025· 1 citedOpen Access
CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial
Communications Biology·2025· 1 citedOpen Access
A critique review of fetal hemoglobin modulators through targeting epigenetic regulators for the treatment of sickle cell disease
Life Sciences·2025· 5 cited
Erythrocytic plasma membrane calcium ATPase (PMCA4b) variations mediate redox imbalance to determine artemisinin sensitivity in malaria
2024
Corrigendum to “Generation of an induced pluripotent stem cell line IGIBi18-A from an Indian patient with rubinstein taybi syndrome” [Stem Cell Res. 78 (2024) 103456]
Stem Cell Research·2024Open Access
A critical review of therapeutic interventions in sickle cell disease: Progress and challenges
Archiv der Pharmazie·2024· 6 citedOpen Access
cRGD-modified hybrid lipopolymeric nanoplexes for gene editing in the posterior segment of the eye
International Journal of Biological Macromolecules·2024· 5 cited
Generation of an induced pluripotent stem cell line IGIBi18-A from an Indian patient with Rubinstein Taybi Syndrome
Stem Cell Research·2024· 1 citedOpen Access
KAT3 mutations impair neural crest migration through EMT regulators <i>snai1b a</i> nd <i>snai2</i> in Rubinstein Taybi Syndrome
2024Open Access
AAV mediated genome engineering with a bypass coagulation factor alleviates the bleeding phenotype in a murine model of hemophilia B
Thrombosis Research·2024· 1 cited
CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial
2024Open Access
Development of pathophysiologically relevant models of sickle cell disease and β-thalassemia for therapeutic studies
Nature Communications·2024· 11 citedOpen Access
Erythrocyte Plasma Membrane Calcium&amp;nbsp;ATPase (PMCA4b) Variations Determine Artemisinin Sensitivity in Malaria: Evidence from Southeast Asian Population
SSRN Electronic Journal·2024Open Access
Scalable noninvasive amplicon-based precision sequencing (SNAPseq) for genetic diagnosis and screening of β-thalassemia and sickle cell disease using a next-generation sequencing platform
Frontiers in Molecular Biosciences·2023· 5 citedOpen Access
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Frequent Co-authors

Sangam Giri Goswami(17), Srinivasan Chandrasegaran(13), Pragya Gupta(12), Nupur Bhargava(10), Suman Jain(8), Priya Thakur(8), Vinodh Saravanakumar(8), Narayana Annaluru(7), Karthikeyan Kandavelou(6), Vinod Scaria(5), Geeta Kumari(5), Arvinden VR(5), Shailja Singh(5), Viktoriya London(4), Rahul C. Bhoyar(4), Sridhar Sivasubbu(4), Shashank Jaitly(4), Padma Gunda(4), Swati Garg(4), Mehwish Nafiz(4)