Srinivasan Chandrasegaran

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index7.3kcitations76works1.02yr avg
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Research Topics

CRISPR and Genetic Engineering(37), Advanced biosensing and bioanalysis techniques(21), DNA and Nucleic Acid Chemistry(20), RNA and protein synthesis mechanisms(18), DNA Repair Mechanisms(9)

Publications76 total

Epidemiology of Human Metapneumovirus (HMPV) in India: a cross-sectional study
The Lancet Regional Health - Southeast Asia·2025· 1 citedOpen Access
Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains
Cell Genomics·2023· 18 citedOpen Access
Metabolic slowdown as the proximal cause of ageing and death
2023· 4 citedOpen Access
CRISPR Correction of the <i>GBA</i> Mutation in Human-Induced Pluripotent Stem Cells Restores Normal Function to Gaucher Macrophages and Increases Their Susceptibility to <i>Mycobacterium tuberculosis</i>
The Journal of Infectious Diseases·2023· 9 citedOpen Access
CRISPR correction of <i>GBA</i> mutation in hiPSCs restores normal function to Gaucher macrophages and increases their susceptibility to <i>Mycobacterium tuberculosis</i>
2022· 1 citedOpen Access
Genome Editing Revolution in Life Sciences
Resonance·2021· 4 citedOpen Access
Rewriting the Genome of the Model Eukaryote Saccharomyces cerevisiae
Resonance·2020· 1 cited
Genome editing of human embryos: to edit or not to edit, that is the question
Journal of Clinical Investigation·2017· 1 citedOpen Access
Design of a synthetic yeast genome
Science·2017· 589 citedOpen Access
Recent advances in the use of ZFN-mediated gene editing for human gene therapy
Cell and Gene Therapy Insights·2017· 31 citedOpen Access
The Era of Synthetic Biology and Genome Engineering: Where No Man Has Gone Before
Journal of Molecular Biology·2016· 3 cited
Origins of Programmable Nucleases for Genome Engineering
Journal of Molecular Biology·2015· 310 citedOpen Access
Erratum to: Rewriting the blueprint of life by synthetic genomics and genome engineering
Genome biology·2015· 1 citedOpen Access
Rewriting the blueprint of life by synthetic genomics and genome engineering
Genome biology·2015· 30 citedOpen Access
TALEN-Mediated Generation and Genetic Correction of Disease-Specific Human Induced Pluripotent Stem Cells
Current Gene Therapy·2014· 64 cited
Total Synthesis of a Functional Designer Eukaryotic Chromosome
Science·2014· 557 citedOpen Access
A CRISPR way to engineer the human genome
Genome Biology·2013· 36 citedOpen Access
Generation and Genetic Engineering of Human Induced Pluripotent Stem Cells Using Designed Zinc Finger Nucleases
Stem Cells and Development·2012· 44 citedOpen Access
The Build-a-Genome Course
Methods in molecular biology·2012· 8 cited
Assembling Large DNA Segments in Yeast
Methods in molecular biology·2012· 38 cited
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Frequent Co-authors

Karthikeyan Kandavelou(12), Sivaprakash Ramalingam(10), Jef D. Boeke(8), Joel S. Bader(8), Narayana Annaluru(8), Sarah M. Richardson(6), Jessica S. Dymond(6), Héloïse Muller(5), Eric M. Cooper(5), Viktoriya London(4), Mala Mani(4), Durai Sundar(4), Marc Ostermeier(4), Y G Kim(3), Jeff Smith(3), Yang‐Gyun Kim(3), Leslie A. Mitchell(3), Giovanni Stracquadanio(3), L Li(3), Louisa P. Wu(3)