Ilyas Chachoua

Bilkent University — Turkey

Medicine · Health Sciences

15h-index1.6kcitations28works1.62yr avg
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Research Topics

Myeloproliferative Neoplasms: Diagnosis and Treatment(17), Kruppel-like factors research(11), Acute Myeloid Leukemia Research(8), Chronic Myeloid Leukemia Treatments(6), Genomics and Chromatin Dynamics(3)

Publications28 total

Contact Unmodified Antisense DNA Biotechnology (CUADb)-Based Oligonucleotide Insecticides and RNA Biocontrols: Molecular Bases and Potential in Plant Protection
Current Issues in Molecular Biology·2026Open Access
A distal CTCF-binding site drives MYC expression plasticity in a negative feed-forward loop
2026Open Access
Extracellular ssDNA from <i>P. tobira</i> Exerts Strong Insecticidal Activity on <i>C. hesperidum</i>
2025Open Access
Single-Cell Microwave Cytometry for Drug Resistance Detection in Cancer
2025Open Access
Editorial: Non-coding RNAs as emerging players in the development, diagnosis, and treatment of cancer
Frontiers in Molecular Biosciences·2024· 1 citedOpen Access
Recent Advances towards the Understanding of Secondary Acute Myeloid Leukemia Progression
Life·2024· 6 citedOpen Access
Recent Advances Towards the Understanding of Secondary Acute Myeloid Leukemia Progression
Preprints.org·2024· 4 citedOpen Access
Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation
Nature Communications·2023· 20 citedOpen Access
Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms
Blood·2022· 43 citedOpen Access
Structural Basis of Oncogenesis by Mutants of Calreticulin
2022· 1 citedOpen Access
Canonical WNT signaling-dependent gating of MYC requires a noncanonical CTCF function at a distal binding site
Nature Communications·2022· 24 citedOpen Access
Author Correction: WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating
Nature Genetics·2020· 7 citedOpen Access
A p53-JAK-STAT connection involved in myeloproliferative neoplasm pathogenesis and progression to secondary acute myeloid leukemia
Blood Reviews·2020· 23 citedOpen Access
MPL mutations in essential thrombocythemia uncover a common path of activation with eltrombopag dependent on W491
Blood·2020· 19 citedOpen Access
WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating
Nature Genetics·2019· 118 cited
Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants
Blood·2019· 94 citedOpen Access
Secreted Mutant Calreticulins As Rogue Cytokines Trigger Thrombopoietin Receptor Activation Specifically in CALR Mutated Cells: Perspectives for MPN Therapy
Blood·2018· 33 cited
Crispr/Cas9 Engineered 61bp Deletion in the Calr Gene of Mice Leads to Development of Thrombocytosis
Blood·2016· 5 cited
Pathologic activation of thrombopoietin receptor and JAK2-STAT5 pathway by frameshift mutants of mouse calreticulin
Leukemia·2016· 41 citedOpen Access
Pathological activation of TpoR and JAK2 STAT5 pathway by frameshift mutants of murine calreticulin
Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B))·2016
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Frequent Co-authors

Stefan N. Constantinescu(18), C. Pecquet(14), William Vainchenker(11), Isabelle Plo(9), Róbert Královics(9), Harini Nivarthi(8), Caroline Marty(8), Jean‐Philippe Defour(8), Gaëlle Vertenoeil(6), Thomas Balligand(6), Emilie Leroy(4), Daniela Pietra(4), Bettina Gisslinger(4), Martin Schalling(4), Mario Cazzola(4), Barbara A. Scholz(4), Mirco Martino(4), Ilias Tzelepis(4), Anita Göndör(4), Didier Vertommen(4)