Giulio Dondio

Gruppo Scienzia Machinale (Italy) — Italy

Neuroscience · Life Sciences

26h-index2.0kcitations80works1.12yr avg
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Research Topics

Neuropeptides and Animal Physiology(29), Pharmacological Receptor Mechanisms and Effects(26), Receptor Mechanisms and Signaling(21), Computational Drug Discovery Methods(10), Histone Deacetylase Inhibitors Research(9)

Publications80 total

4-(5-Chloro-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-yl)benzenesulfonamide: A Novel Polypharmacology Agent to Target Carbonic Anhydrase IX and XII With Improved Selectivity, Wnt/β-Catenin Signaling Pathway, and P-Glycoprotein.
PubMed·2026Open Access
Ferroptosis Induction by a New Pyrrole Derivative in Triple Negative Breast Cancer and Colorectal Cancer
Journal of Medicinal Chemistry·2025· 1 cited
Correction to “Novel <i>N</i>-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as Anticancer Agent”
ACS Pharmacology & Translational Science·2025Open Access
Development of <i>N</i>-(4-(1<i>H</i>-Imidazol-1-yl)phenyl)-4-chlorobenzenesulfonamide, a Novel Potent Inhibitor of β-Catenin with Enhanced Antitumor Activity and Metabolic Stability
Journal of Medicinal Chemistry·2024· 2 cited
SAR Analysis of Novel Coxsackie virus A9 Capsid Binders
Journal of Medicinal Chemistry·2024Open Access
Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents
Bioorganic & Medicinal Chemistry·2024· 3 citedOpen Access
4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses
ACS Infectious Diseases·2024· 2 citedOpen Access
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers
Journal of Pharmaceutical and Biomedical Analysis·2023Open Access
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain
Pharmaceuticals·2023· 8 citedOpen Access
Novel <i>N</i>-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent
ACS Pharmacology & Translational Science·2023· 7 citedOpen Access
Favorable Preclinical Pharmacological Profile of a Novel Antimalarial Pyrrolizidinylmethyl Derivative of 4-amino-7-chloroquinoline with Potent In Vitro and In Vivo Activities
Biomolecules·2023· 4 citedOpen Access
Targeting the Grb2 cSH3 domain: Design, synthesis and biological evaluation of the first series of modulators
Bioorganic Chemistry·2023· 4 citedOpen Access
Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer
Journal of Medicinal Chemistry·2023· 27 citedOpen Access
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents
European Journal of Medicinal Chemistry·2023· 19 citedOpen Access
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo
European Journal of Medicinal Chemistry·2022· 9 cited
Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor
Journal of Medicinal Chemistry·2022· 22 citedOpen Access
CCDC 2162091: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
Novel analgesic/anti-inflammatory agents: 1,5-Diarylpyrrole nitrooxyethyl sulfides and related compounds as Cyclooxygenase-2 inhibitors containing a nitric oxide donor moiety endowed with vasorelaxant properties
European Journal of Medicinal Chemistry·2022· 11 citedOpen Access
Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics
Cancers·2022· 21 citedOpen Access
Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models
ACS Medicinal Chemistry Letters·2020· 25 citedOpen Access
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Frequent Co-authors

Chiara Bigogno(18), Mario Varasi(13), Ciro Mercurio(12), Paola Petrillo(12), Giuseppe Giardina(11), Stefania Vultaggio(8), Saverio Minucci(8), Giuseppe La Regina(7), Ruoli Bai(7), Ernest Hamel(7), Romano Silvestri(7), Giuseppe Petrone(7), Florian Thaler(7), Silvano Ronzoni(7), Antonio Coluccia(6), Marianna Nalli(6), Patrizia Lavia(6), Luca F. Raveglia(6), Paola Misiano(6), Andrea Colombo(6)