Shosaku Numa

Biochemistry, Genetics and Molecular Biology · Life Sciences

83h-index34.4kcitations216works0.02yr avg
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Research Topics

Ion channel regulation and function(56), Receptor Mechanisms and Signaling(45), Metabolism and Genetic Disorders(30), Nicotinic Acetylcholine Receptors Study(30), Microbial Metabolic Engineering and Bioproduction(25)

Publications216 total

Supplementary Material for: Diffusion-Weighted Imaging-Fluid-Attenuated Inversion Recovery Mismatch Is Associated with 90-Day Functional Outcomes in Patients Undergoing Mechanical Thrombectomy
Figshare·2020Open Access
Separation of 1-Acylglycerolphosphate Ai 1-Acylglycerolphosphorylcholine Acyltrai
2016
Isolation and Characterization of the Bovine Corticotropin/β-Lipotropin Precursor Gene
European Journal of Biochemistry·2005· 100 citedOpen Access
Calorimetric Investigation of Interactions Between Purple Membrane And Metallic Ions.
2000
Function of a truncated dihydropyridine receptor as both voltage sensor and calcium channel
Nature·1992· 93 cited
Expression of Ca2+-induced Ca2+ release channel activity from cardiac ryanodine receptor cDNA in Chinese hamster ovary cells
Journal of Molecular and Cellular Cardiology·1992· 3 cited
Calcium channel characteristics conferred on the sodium channel by single mutations
Nature·1992· 783 cited
A single mutation alters the sodium-channel to a calcium-permeable channel.
Max Planck Institute for Plasma Physics·1992
Determinants of sensitivity to tetrodotoxin and saxitoxin of sodium channel-II.
Max Planck Institute for Plasma Physics·1992· 1 cited
Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II
FEBS Letters·1991· 469 citedOpen Access
A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor
FEBS Letters·1991· 130 citedOpen Access
Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics
Nature·1991· 147 cited
Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel.
PubMed·1991· 1 cited
Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel
Proceedings of the Royal Society B Biological Sciences·1991· 126 cited
Single point mutations of the sodium channel drastically reduce the pore permeability without preventing its gating
European Biophysics Journal·1991· 61 cited
Primary structure and functional expression from complementary DNA of a brain calcium channel
Nature·1991· 868 cited
Functional expression from cloned cDNAs of glutamate receptor species responsive to kainate and quisqualate.
The Japanese Journal of Pharmacology·1991· 3 citedOpen Access
Selective coupling of different muscarinic acetylcholine receptors to neuronal calcium currents in DNA-transfected cells
Proceedings of the Royal Society B Biological Sciences·1990· 53 cited
Spontaneous and agonist-induced openings of an acetylcholine receptor channel composed of bovine muscle ?-, ? and ?-subunits
Pflügers Archiv - European Journal of Physiology·1990· 51 cited
Primary structure and functional expression from cDN A of the cardiac ryanodine receptor/calcium release channel
FEBS Letters·1990· 347 citedOpen Access
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Frequent Co-authors

Masaharu Noda(22), Tadaaki Hirose(16), Hideo Takahashi(14), Tsutomu Tanabe(11), Seiichi Inayama(11), Masayoshi Mishina(9), Keiji Imoto(9), Yasuji Furutani(9), Atsushi Mikami(7), Tomoyuki Takahashi(7), Mitsuyoshi Toyosato(7), Tai Kubo(7), Hiroshi Takeshima(6), Kenji Kangawa(6), Hisayuki Matsuo(6), Takashi Miyata(6), Walter Stühmer(6), Harukazu Suzuki(6), Bert Sakmann(6), Kazuhiko Fukuda(6)