Yasuji Furutani

Sumitomo Dainippon Pharma (Japan) — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index6.1kcitations40works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(15), Nicotinic Acetylcholine Receptors Study(7), Pharmacological Effects and Assays(7), Immune Response and Inflammation(4), Ion channel regulation and function(4)

Publications40 total

Sphingomyelin Deacylase, the Enzyme Involved in the Pathogenesis of Atopic Dermatitis, Is Identical to the β-Subunit of Acid Ceramidase
International Journal of Molecular Sciences·2020· 11 citedOpen Access
P3‐435: Novel benzodiazepine receptor ligand AC‐4402 is an inverse agonist for GABAAR with pro‐cognitive effect in vivo
Alzheimer s & Dementia·2011
Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models
Cancer Chemotherapy and Pharmacology·2008· 55 cited
Discovery of a Novel and Potent Human and Rat β<sub>3</sub>‐Adrenergic Receptor Agonist, [3‐[(2R)‐[ [(2R)‐(3‐Chlorophenyl)‐2‐hydroxyethyl]amino]propyl]‐1H‐indol‐7‐yloxy] acetic Acid.
ChemInform·2005
Tryptamine‐Based Human β<sub>3</sub>‐Adrenergic Receptor Agonists. Part 1. SAR Studies of the 7‐Position of the Indole Ring.
ChemInform·2005
Tryptamine‐Based Human β<sub>3</sub>‐Adrenergic Receptor Agonists. Part 2. SAR of the Methylene Derivatives.
ChemInform·2005
Tryptamine-based human β3-adrenergic receptor agonists. Part 3: Improved oral bioavailability via modification of the sulfonamide moiety
Bioorganic & Medicinal Chemistry Letters·2005· 11 citedOpen Access
Discovery of a Novel and Potent Human and Rat .BETA.3-Adrenergic Receptor Agonist, [3-[(2R)-[[(2R)-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1H-indol-7-yloxy]acetic Acid
Chemical and Pharmaceutical Bulletin·2005· 35 citedOpen Access
Tryptamine-based human β3-adrenergic receptor agonists. Part 2: SAR of the methylene derivatives
Bioorganic & Medicinal Chemistry Letters·2004· 7 citedOpen Access
Discovery of 1,7-cyclized indoles as a new class of potent and highly selective human β3-adrenergic receptor agonists with high cell permeability
Bioorganic & Medicinal Chemistry·2004· 25 cited
Tryptamine-based human β3-adrenergic receptor agonists. Part 1: SAR studies of the 7-position of the indole ring
Bioorganic & Medicinal Chemistry Letters·2004· 9 citedOpen Access
Novel and potent human and rat β3-Adrenergic receptor agonists containing substituted 3-indolylalkylamines
Bioorganic & Medicinal Chemistry Letters·2003· 40 citedOpen Access
Mechanism of Amelioration of Insulin Resistance by β3-Adrenoceptor Agonist AJ-9677 in the KK-A<i>y</i>/Ta Diabetic Obese Mouse Model
Diabetes·2001· 60 cited
[Beta 3-adrenergic receptor].
PubMed·2000
Anti-diabetic and anti-obesity effects of AJ-9677, a novel human β3-adrenoceptor agonist, in genetically obese diabetic mice
The Japanese Journal of Pharmacology·1998· 1 citedOpen Access
Subject Index, Vol. 72, 1996
Cytogenetic and Genome Research·1996Open Access
Human endothelin converting enzyme gene (ECE1) mapped to chromosomal region 1p36.1
Cytogenetic and Genome Research·1996· 7 cited
Molecular characterization of a novel atrial-specific myosin heavy-chain gene expressed in the chick embryo.
PubMed·1995· 19 cited
Essential hypertension and neurovascular compression at the ventrolateral medulla oblongata: MR evaluation.
PubMed·1995· 72 citedOpen Access
Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF)
Biochemical and Biophysical Research Communications·1989· 260 cited
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Frequent Co-authors

Shosaku Numa(12), Masaharu Noda(10), Hiroshi Harada(9), Mayumi Oue(9), Shiro Kato(9), Tadaaki Hirose(8), Seiichi Inayama(8), Mitsue Notake(8), Hideo Takahashi(6), Tsutomu Tanabe(6), Hideki Nomura(6), Kazuhiro Mizuno(6), Masaaki Sawa(6), Hiroshi Tsujiuchi(6), Mitsuyoshi Toyosato(5), Hideo Takahashi(5), Toshikazu Fukui(5), Masaaki Yamada(5), Shinichi Nakamura(5), Hirotaka Tateishi(5)