Mohamed Badr

Menoufia University — Egypt

Chemistry · Physical Sciences

14h-index516citations29works3.62yr avg
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Research Topics

Synthesis and biological activity(10), Cancer therapeutics and mechanisms(8), Quinazolinone synthesis and applications(5), Bioactive Compounds and Antitumor Agents(5), Click Chemistry and Applications(3)

Publications29 total

Proteus mirabilis in ICU Patients: Prevalence, Risk Factors, and Future Expectations of Bloodstream Infections
Cureus·2025Open Access
Unveiling ortho-phenolic Mannich ciprofloxacin-chalcone conjugates with potential antineoplastic activity: synthesis, mechanistic study, in silico docking and molecular dynamic simulation
European Journal of Medicinal Chemistry·2025· 1 cited
Design, Synthesis, and Molecular Docking Studies of Indolo[3,2-c]Quinolines as Topoisomerase Inhibitors
Anti-Cancer Agents in Medicinal Chemistry·2025
Efficiency of Water Kumquat (Fortunella margarita) Extracts Against Hepatotoxicity Induced by Carbendazim in Vitro and In Vivo
Current Research in Nutrition and Food Science Journal·2024Open Access
In Silico and In Vitro Investigation of Cytotoxicity and Apoptosis of Acridine/Sulfonamide Hybrids Targeting Topoisomerases I and II
Pharmaceuticals·2024· 5 citedOpen Access
Design, synthesis and mechanistic study of N-4-Piperazinyl Butyryl Thiazolidinedione derivatives of ciprofloxacin with Anticancer Activity via Topoisomerase I/II inhibition
Scientific Reports·2024· 12 citedOpen Access
Design, Synthesis and Mechanistic Study of New Dual Targeting HDAC/Tubulin Inhibitors
Future Medicinal Chemistry·2024· 7 citedOpen Access
Novel 3-phenylquinazolin-2,4(1H,3H)-diones as dual VEGFR-2/c-Met-TK inhibitors: design, synthesis, and biological evaluation
Scientific Reports·2023· 27 citedOpen Access
Design, synthesis and molecular docking of 1,2,4-triazole schiff base hybrids as tubulin, EGFR inhibitors and apoptosis-inducers
Journal of Molecular Structure·2023· 22 cited
Design and biological evaluation of 3-substituted quinazoline-2,4(1 <i>H</i> ,3 <i>H</i> )-dione derivatives as dual c-Met/VEGFR-2-TK inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry·2023· 28 citedOpen Access
Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition
Bioorganic Chemistry·2023· 27 cited
Synthesis and molecular docking of new N4-piperazinyl ciprofloxacin hybrids as antimicrobial DNA gyrase inhibitors
Molecular Diversity·2022· 23 citedOpen Access
Design, synthesis, in vitro antiproliferative evaluation and in silico studies of new VEGFR-2 inhibitors based on 4-piperazinylquinolin-2(1H)-one scaffold
Bioorganic Chemistry·2022· 25 cited
Chemical constituents from <i>Carica papaya</i> Linn. leaves as potential cytotoxic, EGFR<sup>wt</sup> and aromatase (CYP19A) inhibitors; a study supported by molecular docking
RSC Advances·2022· 36 citedOpen Access
Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors
Bioorganic Chemistry·2021· 31 cited
New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors
Pharmaceuticals·2021· 20 citedOpen Access
Novel antimicrobial ciprofloxacin-pyridinium quaternary ammonium salts with improved physicochemical properties and DNA gyrase inhibitory activity
Medicinal Chemistry Research·2021· 9 cited
Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities
Molecular Diversity·2021· 34 cited
Novel 4-(piperazin-1-yl)quinolin-2(1H)-one bearing thiazoles with antiproliferative activity through VEGFR-2-TK inhibition
Bioorganic & Medicinal Chemistry·2021· 38 citedOpen Access
3-Cyano-2-oxa-pyridines: a promising template for diverse pharmacological activities
Journal of advanced Biomedical and Pharmaceutical Sciences·2021· 19 citedOpen Access
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Frequent Co-authors

Gamal El‐Din A. Abuo‐Rahma(14), Mamdouh F. A. Mohamed(5), Amr K. A. Bass(4), Mona S. El‐Zoghbi(4), Abdelfattah Hassan(4), Heba A. Hassan(3), Mai E. Shoman(3), Mohammed A. S. Abourehab(3), El-Shimaa M. Nageeb(2), Dalia Abdelhamid(2), Hossameldin A. Aziz(2), Ahmed M. M. El‐Saghier(2), Ahmed Mohamed Mosallam(2), Aboubakr H. Abdelmonsef(2), Montaser Sh. A. Shaykoon(2), Alaa M. Hayallah(2), Samar H. Abbas(2), Tarek S. Ibrahim(2), Elshimaa M. N. Abdelhafez(2), Elshaymaa I. Elmongy(2)