Mamdouh F. A. Mohamed

Nile Valley University — SD

Chemistry · Physical Sciences

24h-index1.7kcitations70works5.52yr avg
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Research Topics

Synthesis and biological activity(36), Synthesis and Biological Evaluation(15), Histone Deacetylase Inhibitors Research(11), Cancer therapeutics and mechanisms(9), Protein Degradation and Inhibitors(8)

Publications70 total

S5582 From Pacific Isles to Liver Trials: Unraveling the Toxic Tale of Kava
The American Journal of Gastroenterology·2025
Design, Synthesis, In Silico Docking, Multitarget Bioevaluation and Molecular Dynamic Simulation of Novel Pyrazolo[3,4-d]Pyrimidinone Derivatives as Potential In Vitro and In Vivo Anti-Inflammatory Agents
Pharmaceuticals·2025· 1 citedOpen Access
Novel di-aryl chalcone derived pyrazole linked to methane sulfonyl pharmacophore as potent selective COX-2 inhibitors; design, synthesis, molecular modeling, <i>in vitro</i> and <i>in vivo</i> anti-inflammatory activities
Future Medicinal Chemistry·2025· 6 cited
Synthesis and apoptotic induction of sulfonamide-based chalcone hybrids as first-in-class dual histone deacetylase‑carbonic anhydrase inhibitors with potential anti-tubulin activity
Bioorganic Chemistry·2025· 12 cited
Discovery of novel thiazolopyrimidine derivatives targeting topoisomerase II: Design, synthesis, antiproliferative evaluation, molecular docking and apoptosis inducing activity
Bioorganic Chemistry·2025· 13 cited
Author response for "Amide linked chalcone derivatives, a promising class of compounds with versatile biological effects"
2025
Design, Synthesis and Biological Evaluation of Phenoxyacetic Acid derivatives Linked to Pyrazole Scaffold as PPAR-α/γ Agonists and COX-2 Inhibitors with Dual Antidiabetic/Anti-inflammatory Activities
Journal of Molecular Structure·2025· 9 cited
Novel chalcone candidates as potential in vitro and in vivo anti-inflammatory agents: Synthesis, in silico docking, multitarget bioevaluation and molecular dynamic simulation
Bioorganic Chemistry·2025· 6 cited
Novel benzenesulfonamide derivatives linked to diaryl pyrazole tail as potential carbonic anhydrase II/VII inhibitors with anti-epileptic activity
European Journal of Medicinal Chemistry·2025· 15 cited
Pyrazolo[3,4-d]pyrimidine Scaffold: Synthetic Strategies and Biological Activities
Sphinx journal of Pharmaceutical and Medical Sciences /Sphinx journal of Pharmaceutical and Medical Sciences·2025· 2 cited
Synthesis of the novel selena-3,5,8-triazaacenaphthylenes using p-TsOH as a catalyst and investigation of their anti-cancer activity
Journal of Molecular Structure·2025· 1 cited
A review of recent advances in anticancer activity and SAR of pyrazole derivatives
Archiv der Pharmazie·2025· 16 citedOpen Access
Urban Landfills and Bird Ecology: Evaluating and Protecting Migratory Birds in Tayba Al Hasanab, Khartoum, Sudan
2025
Synthesis, anticancer and anti-inflammatory evaluation of novel quinoxaline-1,3,4-oxadiazole derivatives as EGFR and COX-2 inhibitors
Journal of Molecular Structure·2025· 10 cited
Disclosing the impact of metformin and methotrexate in adjuvant arthritis in female rats: molecular docking and biochemical insights on visfatin
Naunyn-Schmiedeberg s Archives of Pharmacology·2025· 3 cited
Microwave assisted synthesis, biological assessment and in-silico studies of some new 5,5′-(phenylmethylene)bisuracil and dihydropyrido[2,3-d:6,5-d']dipyrimidine derivatives as selective COX-2 inhibitors with potential anti-inflammatory activities
Journal of Molecular Structure·2025· 6 cited
Exploration of anti-inflammatory activity of pyrazolo[3,4-d]pyrimidine/1,2,4-oxadiazole hybrids as COX-2, 5-LOX and NO release inhibitors: Design, synthesis, in silico and in vivo studies
Bioorganic Chemistry·2025· 12 cited
Rationale Design and Synthesis of New Quinazoline Derivatives as DNA Intercalators and Topoisomerase Ii Inhibitors
SSRN Electronic Journal·2025Open Access
Amide linked chalcone derivatives, a promising class of compounds with versatile biological effects
RSC Advances·2025· 7 citedOpen Access
Design, synthesis, and anti-breast cancer activity evaluation of novel 3-cyanopyridine derivatives as PIM-1 inhibitors
Molecular Diversity·2024· 4 citedOpen Access
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Frequent Co-authors

Gamal El‐Din A. Abuo‐Rahma(19), Tarek S. Ibrahim(13), Bahaa G. M. Youssif(7), Amr H. Moustafa(7), Rasha M. Allam(7), Alaa M. Hayallah(6), Mohamed Badr(5), Mostafa Abdelrahman(5), Wael A. A. Fadaly(5), Mohamed T. M. Nemr(5), Amr K. A. Bass(4), Mona S. El‐Zoghbi(4), Montaser Sh. A. Shaykoon(4), Eman A. Ahmed(4), Omran A. Omran(4), Ibrahim M. Salem(4), Salah A. Abdel‐Aziz(3), Ahmed S. Aboraia(3), Ahmad J. Almalki(3), Ehab S. Taher(3)