Brett S. Marro

Scripps Research Institute — United States

Immunology and Microbiology · Life Sciences

11h-index626citations25works131.02yr avg
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Research Topics

Immune Cell Function and Interaction(7), Cancer Immunotherapy and Biomarkers(6), Animal Virus Infections Studies(6), interferon and immune responses(6), Multiple Sclerosis Research Studies(5)

Publications25 total

JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma
Science·2024· 131 citedOpen Access
846 Myeloid reprogramming by JAK inhibition enhances checkpoint blockade immunotherapy
Regular and Young Investigator Award Abstracts·2023Open Access
Abstract 5743: Reprogramming myeloid cells by JAK inhibition to enhance checkpoint blockade immunotherapy
Cancer Research·2023
Myeloid reprogramming by JAK inhibition enhances checkpoint blockade therapy
2022· 6 citedOpen Access
Phenotypic small-molecule screening identifies JAK inhibitors as pharmacologic modulators of T cell exhaustion
The Journal of Immunology·2020
Discovery of Small Molecules for the Reversal of T Cell Exhaustion
Cell Reports·2019· 47 citedOpen Access
A unique variant of lymphocytic choriomeningitis virus that induces pheromone binding protein MUP: Critical role for CTL
Proceedings of the National Academy of Sciences·2019· 5 citedOpen Access
Disrupted CXCR2 Signaling in Oligodendroglia Lineage Cells Enhances Myelin Repair in a Viral Model of Multiple Sclerosis
Journal of Virology·2019· 18 citedOpen Access
Macrophage IFN-I signaling promotes autoreactive T cell infiltration into islets in type 1 diabetes model
JCI Insight·2019· 41 citedOpen Access
Chemokine CXCL10 and Coronavirus-Induced Neurologic Disease
Viral Immunology·2018· 51 citedOpen Access
Reversing T cell Exhaustion Through Discovery of Small Molecules
The Journal of Immunology·2018
Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment
European Journal of Immunology·2018· 44 citedOpen Access
Resistance of human plasmacytoid dendritic CAL-1 cells to infection with lymphocytic choriomeningitis virus (LCMV) is caused by restricted virus cell entry, which is overcome by contact of CAL-1 cells with LCMV-infected cells
Virology·2017· 1 citedOpen Access
Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus
Virology·2017· 3 citedOpen Access
Progression of type 1 diabetes from the prediabetic stage is controlled by interferon-α signaling
Proceedings of the National Academy of Sciences·2017· 68 citedOpen Access
Neutrophils and viral-induced neurologic disease
Clinical Immunology·2016· 22 cited
Type I interferon signaling is essential for cytotoxic T lymphocytes to infiltrate into the pancreatic islet and cause type I diabetes
The Journal of Immunology·2016
Inducible expression of CXCL1 within the CNS amplifies demyelination in pre-clinical models of multiple sclerosis
The Journal of Immunology·2016
Inducible Expression of CXCL1 within the Central Nervous System Amplifies Viral-Induced Demyelination
The Journal of Immunology·2016· 41 citedOpen Access
CXCR2 signaling regulates neuroinflammation in models of viral and autoimmune-induced neurodegenerative disease
eScholarship (California Digital Library)·2015Open Access
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Frequent Co-authors

Thomas E. Lane(12), Michael B. A. Oldstone(11), Jaroslav Žák(7), John R. Teijaro(7), Isaraphorn Pratumchai(5), Luke L. Lairson(5), Jonathan J. Grist(5), Kristi Marquardt(4), Reza Beheshti Zavareh(4), Judith A. Varner(4), Veronika Bachanová(4), Brian C. Ware(4), Craig M. Walsh(3), Dominic D. Skinner(3), Brian M. Weist(2), Bram J. van Raam(2), Long Nguyen(2), P. L. Srinivas(2), Bryan D. Bell(2), Juan Carlos de la Torre(2)