William Jia

Vancouver Biotech (Canada) — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index2.9kcitations137works3.52yr avg
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Research Topics

Virus-based gene therapy research(76), RNA Interference and Gene Delivery(27), Herpesvirus Infections and Treatments(23), Animal Virus Infections Studies(21), CAR-T cell therapy research(14)

Publications137 total

Hypothesis-generating evaluation of multi-armoured oncolytic HSV-1 (VG161) in intrahepatic cholangiocarcinoma: pooled insights from multicentre studies
Gut·2025
Oncolytic virus VG161 in combination with camrelizumab as second-line therapy in patients with advanced primary hepatocellular carcinoma: A phase Ib/IIa clinical study.
Journal of Clinical Oncology·2025
Heterologous prime-boost with an mRNA vaccine and an oncolytic virus enhances tumor regression through overcoming intratumoral immune suppression
Cell Reports·2025· 1 citedOpen Access
Abstract 953: Oncolytic viruses as in situ personalized tumor vaccines for durable efficacy
Cancer Research·2025
An mRNA Vaccine for Herpes Zoster and Its Efficacy Evaluation in Naïve/Primed Murine Models
Vaccines·2025· 2 citedOpen Access
Abstract C005: Tumor vaccines and oncolytic virotherapy: systemic immunity vs. tumor microenvironment
Cancer Research·2024
Abstract PR003: Preventing and treating HPV-related Cancer with mRNA Therapy Expressing A DC-targeting Antigen
Molecular Cancer Therapeutics·2024
A Novel Self‐Amplifying mRNA with Decreased Cytotoxicity and Enhanced Protein Expression by Macrodomain Mutations
Advanced Science·2024· 25 citedOpen Access
Prophylactic Vaccination and Intratumoral Boost with HER2-Expressing Oncolytic Herpes Simplex Virus Induces Robust and Persistent Immune Response against HER2-Positive Tumor Cells
Vaccines·2023· 3 citedOpen Access
mRNA vaccines encoding fusion proteins of monkeypox virus antigens protect mice from vaccinia virus challenge
Nature Communications·2023· 91 citedOpen Access
Vaccines’ New Era-RNA Vaccine
Viruses·2023· 47 citedOpen Access
Data from Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3
2023Open Access
Data from Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3
2023Open Access
Supplementary Figure S1, S2, S3, S4, S5, S6, S7, S8, S9 from Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3
2023Open Access
Supplementary Figure S1, S2, S3, S4, S5, S6, S7, S8, S9 from Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3
2023Open Access
Supplementary Methods from Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice
2023Open Access
Supplementary Figure 1 from Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice
2023Open Access
Supplementary Figure 2 from Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice
2023Open Access
Supplementary Figure 3 from Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice
2023Open Access
Supplementary Figure 1 from Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice
2023Open Access
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Frequent Co-authors

Max S. Cynader(9), Paul S. Rennie(6), Vivian Lam(5), Gerald Krystal(5), Ladan Fazli(5), Ingrid Elisia(4), Luke Bu(4), Xuexian Bu(4), Brandon Cho(3), Mariah Hay(3), Michael Y. Li(3), Elyse Hofs(3), Honglin Luo(3), Andy Eberding(3), Martin Gleave(3), John C. Bell(3), Si Zhang(3), Guang Yang(3), Cleo Lee(2), Hans Adomat(2)