Léo Aubert

Institute for Research in Immunology and Cancer — Canada

Medicine · Health Sciences

16h-index1.4kcitations54works9.52yr avg
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Research Topics

Acute Myeloid Leukemia Research(7), Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities(6), Protein Degradation and Inhibitors(6), Advanced biosensing and bioanalysis techniques(5), Cancer, Hypoxia, and Metabolism(4)

Publications53 total

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype
Advanced Science·2025· 1 citedOpen Access
IL1RAP is an immunotherapeutic target for normal karyotype triple-mutated acute myeloid leukemia
Biomarker Research·2025· 4 citedOpen Access
PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma
Nature Communications·2025· 14 citedOpen Access
Acid-exposed and hypoxic cancer cells do not overlap but are interdependent for unsaturated fatty acid resources
Nature Communications·2024· 6 citedOpen Access
Immunotherapeutic targeting of surfaceome heterogeneity in AML
Cell Reports·2024· 23 citedOpen Access
Tumor acidosis-induced DNA damage response and tetraploidy enhance sensitivity to ATM and ATR inhibitors
EMBO Reports·2024· 9 citedOpen Access
The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression
Cell Reports·2023· 8 citedOpen Access
CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216
Blood Advances·2023· 25 citedOpen Access
SPAT: Surface Protein Annotation Tool
2023· 3 citedOpen Access
Identification of Novel Cell Surface Therapeutic Targets for <i>KMT2A</i>-Rearranged Acute Myeloid Leukemia
Blood·2022
Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells
Journal of Experimental & Clinical Cancer Research·2022· 18 citedOpen Access
3173 – HUMAN MODELS OF PEDIATRIC CBFA2T3-GLIS2 ACUTE MEGAKARYOBLASTIC LEUKEMIA CONTRIBUTE TO UNCOVER THERAPEUTIC VULNERABILITIES
Experimental Hematology·2022
Targeting copper metabolism to defeat KRAS-driven colorectal cancer
Molecular & Cellular Oncology·2020· 11 citedOpen Access
3058 – SURFACE PROTEOMICS REVEALS NOVEL POTENTIAL AML ANTIGENS FOR IMMUNOTHERAPEUTIC TARGETING
Experimental Hematology·2020
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
Nature Communications·2020· 304 citedOpen Access
NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay
Cell Reports·2020· 44 citedOpen Access
Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion
Molecular & Cellular Proteomics·2019· 18 citedOpen Access
Human models of NUP98-KDM5A megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities
Blood Advances·2019· 30 citedOpen Access
ProNGF increases breast tumor aggressiveness through functional association of TrkA with EphA2
Cancer Letters·2019· 37 citedOpen Access
Coordination of Pro- and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion
Blood·2018
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Frequent Co-authors

Philippe P. Roux(19), Guy Sauvageau(8), Cyril Corbet(7), Louis Thérêt(7), Jalila Chagraoui(6), Jean-François Spinella(6), Josée Hébert(6), Vincent‐Philippe Lavallée(6), Geneviève Lavoie(5), Nadine Mayotte(5), Patrick Gendron(5), Véronique Lisi(5), Éric Audemard(5), H Arroyo(5), Sami Nourreddine(4), Louis Gaboury(4), Robert‐Alain Toillon(4), Azer Farah(4), Marie-Ève Bordeleau(4), Isabel Boivin(4)