Jenny M. Pedersen

Medicine · Health Sciences

8h-index969citations15works0.02yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(8), Pharmacological Effects and Toxicity Studies(5), Pancreatic function and diabetes(4), Liver physiology and pathology(4), Pharmacogenetics and Drug Metabolism(3)

Publications15 total

Fluid Dynamic Modeling to Support the Development of Flow-Based Hepatocyte Culture Systems for Metabolism Studies
UNC Libraries·2024Open Access
Hepatocyte size fractionation allows dissection of human liver zonation
Journal of Cellular Physiology·2021· 24 citedOpen Access
Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective
Clinical Pharmacology & Therapeutics·2018· 112 citedOpen Access
Xenobiotic Metabolism in Alginate-Encapsulated Primary Human Hepatocytes Over Long Timeframes
Applied In Vitro Toxicology·2018· 8 citedOpen Access
Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)
European Journal of Pharmaceutical Sciences·2017· 33 cited
Fluid Dynamic Modeling to Support the Development of Flow-Based Hepatocyte Culture Systems for Metabolism Studies
Frontiers in Bioengineering and Biotechnology·2016· 18 citedOpen Access
Streamlining metabolite identification and toxicity testing using alginate supported 3D culture of primary hepatocytes
Toxicology Letters·2016
Liver bioreactor and incorporation of metabolism and biokinetics into the integrated cell-based toxicity system
Toxicology Letters·2016
Liver bioreactor as an in vitro metabolism system for quantitative in vitro to in vivo extrapolation
Toxicology Letters·2014· 1 cited
Early Identification of Clinically Relevant Drug Interactions With the Human Bile Salt Export Pump (BSEP/ABCB11)
Toxicological Sciences·2013· 145 citedOpen Access
Biliary Drug Excretion and Drug-drug Interactions in Sandwich Cultured Human Hepatocytes Predicted from Inverted Membrane Vesicles and Targeted Proteomics
2013
ATP-Binding-Cassette Transporters in Biliary Efflux and Drug-Induced Liver Injury
KTH Publication Database DiVA (KTH Royal Institute of Technology)·2013· 3 citedOpen Access
Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs
Pharmaceutical Research·2009· 311 cited
Structural Requirements for Drug Inhibition of the Liver Specific Human Organic Cation Transport Protein 1
Journal of Medicinal Chemistry·2008· 188 citedOpen Access
Prediction and Identification of Drug Interactions with the Human ATP-Binding Cassette Transporter Multidrug-Resistance Associated Protein 2 (MRP2; ABCC2)
Journal of Medicinal Chemistry·2008· 126 citedOpen Access

Frequent Co-authors

Per Artursson(7), Melvin E. Andersen(6), Harvey J. Clewell(6), Miyoung Yoon(6), Christel A. S. Bergström(5), Martin B. Phillips(5), Jeffrey M. Macdonald(5), Pär Matsson(4), Janet Hoogstraate(4), Ulf Norinder(3), Edward L. LeCluyse(3), Yoo-Sik Shim(3), Erin Burgunder(3), David K. Billings(3), Agneta Norén(2), Yurong Lai(2), Johan Palm(2), Vaibhav Hans(2), Glenn M. Walker(2), Jeffrey Enders(2)