Martin B. Phillips

University of North Carolina at Chapel Hill — United States

Environmental Science · Physical Sciences

14h-index654citations30works0.02yr avg
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Research Topics

Effects and risks of endocrine disrupting chemicals(13), Carcinogens and Genotoxicity Assessment(7), Computational Drug Discovery Methods(6), Pharmacogenetics and Drug Metabolism(5), 3D Printing in Biomedical Research(5)

Publications30 total

Fluid Dynamic Modeling to Support the Development of Flow-Based Hepatocyte Culture Systems for Metabolism Studies
UNC Libraries·2024Open Access
Biomarkers: key to exposure reconstruction
AccessScience·2022Open Access
The TTC Data Mart: An interactive browser for threshold of toxicological concern calculations
Computational Toxicology·2020· 3 citedOpen Access
The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay
Toxicology and Applied Pharmacology·2019· 16 citedOpen Access
Xenobiotic Metabolism in Alginate-Encapsulated Primary Human Hepatocytes Over Long Timeframes
Applied In Vitro Toxicology·2018· 8 citedOpen Access
Excretion of Di-2-ethylhexyl phthalate (DEHP) metabolites in urine is related to body mass index because of higher energy intake in the overweight and obese
Environment International·2018· 42 citedOpen Access
Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays
Toxicology in Vitro·2018· 32 citedOpen Access
Alginate-encapsulated primary human hepatocyte culture system to increase the accuracy of the predicted in vivo half-life of low clearance compounds
Drug Metabolism and Pharmacokinetics·2018
Incorporation of human relevant metabolism into fit-for-purpose in vitro assays for safety assessment: Case study with bioactivated mutagens
Toxicology Letters·2017
Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates
Chemosphere·2017· 29 citedOpen Access
Estimating Methylmercury Intake for the General Population of South Korea Using Physiologically Based Pharmacokinetic Modeling
Toxicological Sciences·2017· 10 citedOpen Access
The first steps towards a novel 3D flow-based bioreactor in vitro system for compound induced (chronic) liver toxicity
2017
Fluid Dynamic Modeling to Support the Development of Flow-Based Hepatocyte Culture Systems for Metabolism Studies
Frontiers in Bioengineering and Biotechnology·2016· 18 citedOpen Access
Streamlining metabolite identification and toxicity testing using alginate supported 3D culture of primary hepatocytes
Toxicology Letters·2016
Liver bioreactor and incorporation of metabolism and biokinetics into the integrated cell-based toxicity system
Toxicology Letters·2016
Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction
PLoS Computational Biology·2016· 47 citedOpen Access
Reconstructing exposures from biomarkers using exposure-pharmacokinetic modeling – A case study with carbaryl
Regulatory Toxicology and Pharmacology·2015· 14 cited
Biomarkers: key to exposure reconstruction
AccessScience·2015
A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput <i>in Vitro</i> Chemical Screening Based on Adverse Outcome Pathways
Environmental Health Perspectives·2015· 32 citedOpen Access
Uses of NHANES Biomarker Data for Chemical Risk Assessment: Trends, Challenges, and Opportunities
Environmental Health Perspectives·2015· 107 citedOpen Access
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Frequent Co-authors

Miyoung Yoon(15), Yu‐Mei Tan(10), Harvey J. Clewell(10), Melvin E. Andersen(8), Jon R. Sobus(7), Daniel T. Chang(6), Chris Grulke(5), Michael‐Rock Goldsmith(5), Jenny M. Pedersen(5), Jeffrey M. Macdonald(5), Lisa A. Peterson(4), Jeremy A. Leonard(4), Chantel I. Nicolas(4), Rebecca A. Clewell(4), David K. Billings(4), Pergentino Balbuena(4), Raina D. Brooks(3), Rogelio Tornero‐Velez(3), Kristin Isaacs(3), Mathilde M. Sullivan(3)