Roselyne Castonguay

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index1.3kcitations40works31.02yr avg
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Research Topics

TGF-β signaling in diseases(13), Muscle Physiology and Disorders(9), Sulfur Compounds in Biology(6), Amino Acid Enzymes and Metabolism(6), Metabolism, Diabetes, and Cancer(5)

Publications40 total

Muscle-derived myostatin is a major endocrine driver of follicle-stimulating hormone synthesis
Science·2025· 31 citedOpen Access
Myostatin is a major endocrine driver of follicle-stimulating hormone synthesis
2023· 5 citedOpen Access
Supplementary Table 1 from ALK1-Fc Inhibits Multiple Mediators of Angiogenesis and Suppresses Tumor Growth
2023Open Access
Data from ALK1-Fc Inhibits Multiple Mediators of Angiogenesis and Suppresses Tumor Growth
2023Open Access
Data from ALK1-Fc Inhibits Multiple Mediators of Angiogenesis and Suppresses Tumor Growth
2023Open Access
Supplementary Table 1 from ALK1-Fc Inhibits Multiple Mediators of Angiogenesis and Suppresses Tumor Growth
2023Open Access
The orphan ligand, activin C, signals through activin receptor-like kinase 7
eLife·2022· 35 citedOpen Access
Author response: The orphan ligand, activin C, signals through activin receptor-like kinase 7
2022Open Access
Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension
Scientific Reports·2022· 87 citedOpen Access
The orphan ligand, Activin C, signals through activin receptor-like kinase 7
2022· 1 citedOpen Access
Structures of activin ligand traps using natural sets of type I and type II TGFβ receptors
iScience·2021· 16 citedOpen Access
Functionally diverse heteromeric traps for ligands of the transforming growth factor-β superfamily
Scientific Reports·2021· 10 citedOpen Access
ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders
Journal of Clinical Investigation·2021· 32 citedOpen Access
1937-P: ALK-7: A Validated Target for the Treatment of Obesity
Diabetes·2020
Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease
Scientific Reports·2019· 49 citedOpen Access
Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity.
PubMed·2019· 37 cited
Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity
Proceedings of the National Academy of Sciences·2019· 62 citedOpen Access
Follistatin-288-Fc Fusion Protein Promotes Localized Growth of Skeletal Muscle
Journal of Pharmacology and Experimental Therapeutics·2018· 26 citedOpen Access
ACE-083, a locally-acting TGF-β; superfamily ligand trap, increases muscle mass and strength in a mouse model of Duchenne muscular dystrophy
Neuromuscular Disorders·2016· 3 cited
ACE-083 increases muscle hypertrophy and strength in C57BL/6 mice
Neuromuscular Disorders·2015· 6 cited
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Frequent Co-authors

R. Scott Pearsall(18), Ravindra Kumar(17), Asya V. Grinberg(16), Dianne Sako(12), Jeffrey W. Keillor(11), Aaron W. Mulivor(10), Christian Lherbet(10), Kathryn Underwood(8), Jasbir Seehra(8), M. Cannell(8), Nicolas Solban(7), Eileen G. Pobre(7), Travis Monnell(7), Dianne Mitchell(6), Jeffrey A. Ucran(6), Monique V. Davies(6), Rosa Grenha(6), Erich J. Goebel(6), Thomas B. Thompson(6), Katia Liharska(6)