Gilles P. van Wezel

Leiden University — Netherlands

Medicine · Health Sciences

65h-index23.0kcitations313works14.82yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(189), Genomics and Phylogenetic Studies(94), RNA and protein synthesis mechanisms(41), Bacterial Genetics and Biotechnology(40), Plant-Microbe Interactions and Immunity(33)

Publications309 total

Disentangling the molecular mechanisms of disease suppression by endophytic Flavobacterium sp. 98
Microbiological Research·2025Open Access
The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in Streptomyces
PLoS Biology·2025Open Access
gutSMASH 2.0: Extended Identification of Primary Metabolic Gene Clusters From the Human Gut Microbiota
Journal of Molecular Biology·2025Open Access
Essential and dispensable domains of DivIVA for walled growth in filamentous Actinomycetota
Open Biology·2025Open Access
Serotonin modulation of metabolism and stress response in Pseudomonas fluorescens
BMC Biology·2025Open Access
Paenitracins, a novel family of bacitracin-type nonribosomal peptide antibiotics produced by plant-associated <i>Paenibacillus</i> species
2025Open Access
Construction and Diversification of Natural Product Biosynthetic Gene Clusters at High Efficiency and Accuracy
ACS Synthetic Biology·2025Open Access
Author response for "Essential and dispensable domains of DivIVA for walled growth in filamentous Actinomycetota"
2025
Morphological plasticity of endophytic <i>Chitinophaga pinensis</i>
2025Open Access
Defining the minimal structural requirements of DivIVA in filamentous Actinomycetota
2025Open Access
Genome mining based on transcriptional regulatory networks uncovers a novel locus involved in desferrioxamine biosynthesis
PLoS Biology·2025· 6 citedOpen Access
Antifungal biosynthesis by root-associated <i>Streptomyces</i> and <i>Pseudomonas</i> is elicited upon plant colonization
2025· 1 citedOpen Access
antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation
Nucleic Acids Research·2025· 265 citedOpen Access
Biomimetic Total Synthesis and Paired Omics Identify an Intermolecular Diels–Alder Reaction as the Key Step in Lugdunomycin Biosynthesis
Journal of the American Chemical Society·2025· 1 citedOpen Access
Serotonin modulation of metabolism and stress response in <i>Pseudomonas fluorescens</i>
2025
Regulatory Genes as Beacons for Discovery and Prioritization of Biosynthetic Gene Clusters in <i>Streptomyces</i>
Biochemistry·2025· 2 citedOpen Access
Total Synthesis, Structure Elucidation, and Bioactivity Evaluation of the Cyclic Lipopeptide Natural Product Paenilipoheptin A
Organic Letters·2025· 6 citedOpen Access
The stomatin-like protein StlP organizes membrane microdomains to govern polar growth in filamentous actinobacteria under hyperosmotic stress
Nature Communications·2025· 3 citedOpen Access
Exploring the Chemical Space of <i>Paenibacillus</i> NRPs and Discovery of Paenilipoheptin B
Organic Letters·2025· 5 citedOpen Access
New solutions for antibiotic discovery: Prioritizing microbial biosynthetic space using ecology and machine learning
PLoS Biology·2025· 9 citedOpen Access
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Frequent Co-authors

Marnix H. Medema(9), Sébastien Rigali(6), Fritz Titgemeyer(5), Kai Blin(4), Barbara R. Terlouw(4), Eric J. N. Helfrich(4), Dennis Claessen(4), Sharief Barends(4), Chao Du(4), Palanisamy Uma Maheswari(4), J. Reedijk(4), Henk K. Koerten(4), Bjørn A. Traag(4), Young Hae Choi(4), Simon J. Shaw(3), Alexander Kloosterman(3), Tilmann Weber(3), Hannah E. Augustijn(3), Friederike Biermann(3), Víctor J. Carrión(3)