Zoe Siemienski

University of Florida — United States

Medicine · Health Sciences

10h-index684citations14works0.02yr avg
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Research Topics

Amyotrophic Lateral Sclerosis Research(7), Neurogenetic and Muscular Disorders Research(5), Muscle Physiology and Disorders(4), Virus-based gene therapy research(3), Genetic Neurodegenerative Diseases(3)

Publications14 total

Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3
Acta Neuropathologica Communications·2018· 22 citedOpen Access
Additional file 3: of Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3
Figshare·2018Open Access
Additional file 1: of Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3
Figshare·2018Open Access
Retraction Note: Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype
Acta Neuropathologica Communications·2017· 2 citedOpen Access
RETRACTED ARTICLE: Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype
Acta Neuropathologica Communications·2016· 12 citedOpen Access
Heterogeneity of Matrin 3 in the developing and aging murine central nervous system
The Journal of Comparative Neurology·2016· 16 citedOpen Access
Microglia-specific targeting by novel capsid-modified AAV6 vectors
Molecular Therapy — Methods & Clinical Development·2016· 118 citedOpen Access
Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice
Molecular Neurodegeneration·2015· 57 citedOpen Access
Substantially elevating the levels of αB‐crystallin in spinal motor neurons of mutant <scp>SOD</scp>1 mice does not significantly delay paralysis or attenuate mutant protein aggregation
Journal of Neurochemistry·2014· 12 cited
Widespread and Efficient Transduction of Spinal Cord and Brain Following Neonatal AAV Injection and Potential Disease Modifying Effect in ALS Mice
Molecular Therapy·2014· 77 citedOpen Access
Experimental Mutagenesis of Huntingtin to Map Cleavage Sites: Different Outcomes in Cell and Mouse Models
Journal of Huntington s Disease·2014· 2 cited
Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain
PLoS ONE·2013· 210 citedOpen Access
Comment on “ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models”
Science·2013· 137 citedOpen Access
Analysis of Proteolytic Processes and Enzymatic Activities in the Generation of Huntingtin N-Terminal Fragments in an HEK293 Cell Model
PLoS ONE·2012· 19 citedOpen Access

Frequent Co-authors

David Borchelt(12), Susan Fromholt(8), Hilda Brown(8), Todd E. Golde(6), Christina M. Moloney(6), Sruti Rayaprolu(6), John Howard(6), Mariela Cabrera(6), Colin Duffy(6), Jada Lewis(6), Keith Crosby(5), Matt Collins(5), Dave Miller(5), Paramita Chakrabarty(4), Awilda M. Rosario(4), Pedro E. Cruz(4), Carolina Ceballos‐Diaz(4), Guilian Xu(3), Christopher Janus(3), Yona Levites(2)