Hans Iding

Roche (Switzerland) — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.5kcitations60works3.82yr avg
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Research Topics

Enzyme Catalysis and Immobilization(35), Chemical Synthesis and Analysis(12), Microbial Metabolic Engineering and Bioproduction(11), Biochemical Acid Research Studies(8), Asymmetric Hydrogenation and Catalysis(6)

Publications60 total

Data-Driven Construction of an Imine Reductase Library Capable of Broad-Scope Reductive Amination at Equimolar Substrate Concentrations
2026Open Access
Stereoselective Synthesis of <i>trans</i>-3-Amino-2,2,4,4-tetramethylcyclobutanol
Organic Letters·2025· 1 cited
The Swiss Industrial Biocatalysis Consortium (SIBC) turns 20!
CHIMIA International Journal for Chemistry·2025Open Access
Data-Driven Construction of an Imine Reductase Library Capable of Broad-Scope Reductive Amination at Equimolar Substrate Concentrations
2024Open Access
Efficient Enzymatic Synthesis of Carbamates in Water Using Promiscuous Esterases/Acyltransferases
Angewandte Chemie International Edition·2024· 5 citedOpen Access
Effiziente enzymatische Synthese von Carbamaten in Wasser durch promiskuitive Esterasen/Acyltransferasen
Angewandte Chemie·2024Open Access
Excelzyme: A Swiss University-Industry Collaboration for Accelerated Biocatalyst Development
CHIMIA International Journal for Chemistry·2024· 3 citedOpen Access
Biocatalyst Immobilization and Process Intensification: Production of (<i>S</i>)-Piperazine-2-carboxylic Acid Dihydrochloride
Organic Process Research & Development·2024· 7 cited
Effective engineering of a ketoreductase for the biocatalytic synthesis of an ipatasertib precursor
Communications Chemistry·2024· 20 citedOpen Access
Sustainable Drug Substance Processes Enabled by Catalysis
2024· 2 citedOpen Access
Asymmetric Synthesis of <i>N</i>-Alkyl Amino Acids through a Biocatalytic Dynamic Kinetic Resolution of PEGylated <i>N</i>-Alkyl Amino Esters
Organic Letters·2023· 1 cited
CCDC 2120953: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
Stereoselective Synthesis of the IDO Inhibitor Navoximod
The Journal of Organic Chemistry·2022· 13 cited
Screening methods for enzyme-mediated alcohol oxidation
Scientific Reports·2022· 10 citedOpen Access
Development of the Commercial Manufacturing Process for Ipatasertib
CHIMIA International Journal for Chemistry·2021· 12 citedOpen Access
Towards the enzymatic synthesis of phosphorothioate containing LNA oligonucleotides
Bioorganic & Medicinal Chemistry Letters·2021· 28 cited
Cover Feature: Multi‐faceted Set‐up of a Diverse Ketoreductase Library Enables the Synthesis of Pharmaceutically‐relevant Secondary Alcohols (6/2021)
ChemCatChem·2021Open Access
Multi‐faceted Set‐up of a Diverse Ketoreductase Library Enables the Synthesis of Pharmaceutically‐relevant Secondary Alcohols
ChemCatChem·2020· 25 cited
Asymmetric Biocatalytic Synthesis of 1‐Aryltetrahydro‐β‐carbolines Enabled by “Substrate Walking”
Chemistry - A European Journal·2020· 23 citedOpen Access
Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors
Journal of Medicinal Chemistry·2020· 50 cited
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Frequent Co-authors

Beat Wirz(18), Dennis Wetzl(12), Steven P. Hanlon(11), Uwe T. Bornscheuer(7), Martina Pohl(6), Harald Gröger(5), Francis Gosselin(5), Radka Šnajdrová(4), Ιoannis V. Pavlidis(4), Martin S. Weiß(4), Paul Spurr(4), Petra Siegert(4), Ayhan S. Demir(4), Stephan Bachmann(4), Kurt Puentener(4), Thomas Dünnwald(3), Michael Müller(3), René Trussardi(3), Ulrich Zutter(3), Rebecca Buller(3)