Nicholas A. Flavahan

Johns Hopkins University — United States

Medicine · Health Sciences

54h-index9.7kcitations169works0.32yr avg
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Research Topics

Nitric Oxide and Endothelin Effects(59), Receptor Mechanisms and Signaling(53), Neuropeptides and Animal Physiology(14), Systemic Sclerosis and Related Diseases(13), Pharmacological Effects and Assays(13)

Publications169 total

α2 adrenoceptors, cold-induced vasoconstriction, and Raynaud’s phenomenon
Cell Genomics·2025Open Access
The Normal Structure and Function of the Cutaneous Vascular System
2024
A Mechanistic Approach to Understanding and Preventing the Vasculopathy of Raynaud’s Phenomenon
2024· 1 cited
Cooling‐induced cutaneous vasodilatation is mediated by small‐conductance, calcium‐activated potassium channels in tail arteries from male mice
Physiological Reports·2023· 5 citedOpen Access
New mechanism-based approaches to treating and evaluating the vasculopathy of scleroderma
Current Opinion in Rheumatology·2021· 9 cited
Dissecting the Cellular Mechanism of Prostacyclin Analog Iloprost in Reversing Vascular Dysfunction in Scleroderma
Arthritis & Rheumatology·2020· 37 citedOpen Access
Cooling-induced dilatation of cutaneous arteries is mediated by increased myoendothelial communication
American Journal of Physiology-Heart and Circulatory Physiology·2020· 7 citedOpen Access
Potential pitfalls in analyzing structural uncoupling of eNOS: aging is not associated with increased enzyme monomerization
American Journal of Physiology-Heart and Circulatory Physiology·2018· 14 citedOpen Access
Superoxide inhibition restores endothelium-dependent dilatation in aging arteries by enhancing impaired adherens junctions
American Journal of Physiology-Heart and Circulatory Physiology·2018· 20 citedOpen Access
Impaired activity of adherens junctions contributes to endothelial dilator dysfunction in ageing rat arteries
The Journal of Physiology·2017· 23 citedOpen Access
In Development—A New Paradigm for Understanding Vascular Disease
Journal of Cardiovascular Pharmacology·2017· 17 citedOpen Access
Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking‐Dependent and Crosslinking‐Independent Functions
Journal of the American Heart Association·2017· 80 citedOpen Access
Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41
Physiological Genomics·2016· 429 citedOpen Access
Raynaud’s Phenomenon
New England Journal of Medicine·2016· 399 cited
Local renin-angiotensin system mediates endothelial dilator dysfunction in aging arteries
American Journal of Physiology-Heart and Circulatory Physiology·2016· 34 citedOpen Access
Immature endothelial cells initiate endothelin‐mediated constriction of newborn arteries
The Journal of Physiology·2016· 7 citedOpen Access
Endothelial Adherens Junctions and Endothelial Dysfunction in Aging Arteries
The FASEB Journal·2016· 2 cited
Microbial short chain fatty acid (SCFA) metabolites lower blood pressure (BP) via endothelial G‐protein coupled receptor 41 (Gpr41)
The FASEB Journal·2016
Intrauterine Stress Disrupts the Early Postnatal Maturation of Arterial Endothelium
The FASEB Journal·2016· 1 cited
Immature Endothelial Cells Initiate Endothelin‐Mediated Constriction of Newborn Arteries
The FASEB Journal·2016
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Frequent Co-authors

Sheila Flavahan(14), Maqsood A. Chotani(8), Srabani Mitra(7), Paul M. Vanhoutte(6), Sayan Mitra(6), Dan E. Berkowitz(5), Ali H. Eid(5), Simon Bailey(4), Baogen Y. Su(4), Jochen Steppan(3), Hiroaki Shimokawa(3), Pascal J. Goldschmidt‐Clermont(3), Lakshmi Santhanam(3), Marc K. Halushka(3), Daijiro Hori(2), Fredrick M. Wigley(2), Thomas J. Rimele(2), Herbert E. Gregg(2), K. Reed Clark(2), Gautam Sikka(2)