Niki S.C. Wong

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index1.4kcitations25works0.02yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(17), Monoclonal and Polyclonal Antibodies Research(9), Glycosylation and Glycoproteins Research(7), CRISPR and Genetic Engineering(5), Virus-based gene therapy research(4)

Publications25 total

28S rRNA is inducibly pseudouridylated by the mTOR pathway translational control in CHO cell cultures
Journal of Biotechnology·2014· 25 citedOpen Access
28S rRNA is inducibly pseudouridylated by the mTOR pathway translational control in CHO cell cultures
DSpace@MIT (Massachusetts Institute of Technology)·2014Open Access
Understanding translational control mechanisms of the mTOR pathway in CHO cells by polysome profiling
New Biotechnology·2013· 17 cited
Translatome analysis of CHO cells to identify key growth genes
Journal of Biotechnology·2013· 29 cited
Combined in silico modeling and metabolomics analysis to characterize fed‐batch CHO cell culture
Biotechnology and Bioengineering·2012· 203 cited
Rapid characterization of protein productivity and production stability of CHO cells by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry
Rapid Communications in Mass Spectrometry·2011· 19 cited
Metabolomics-based identification of apoptosis-inducing metabolites in recombinant fed-batch CHO culture media
Journal of Biotechnology·2010· 58 cited
Profiling of <i>N</i>‐glycosylation gene expression in CHO cell fed‐batch cultures
Biotechnology and Bioengineering·2010· 51 cited
Two‐dimensional difference fluorescence gel electrophoresis to verify the scale‐up of a non‐affinity‐based downstream process for isolation of a therapeutic recombinant antibody
Electrophoresis·2010· 13 cited
An investigation of intracellular glycosylation activities in CHO cells: Effects of nucleotide sugar precursor feeding
Biotechnology and Bioengineering·2010· 137 cited
Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: Overexpression of malate dehydrogenase II
Journal of Biotechnology·2010· 95 cited
Engineering mammalian cells in bioprocessing – current achievements and future perspectives
Biotechnology and Applied Biochemistry·2010· 133 cited
Rapid characterization of high/low producer CHO cells using matrix‐assisted laser desorption/ionization time‐of‐flight
Rapid Communications in Mass Spectrometry·2010· 19 cited
Metabolomics profiling of extracellular metabolites in recombinant Chinese Hamster Ovary fed‐batch culture
Rapid Communications in Mass Spectrometry·2009· 75 cited
Two-dimensional fluorescence difference gel electrophoresis for comparison of affinity and non-affinity based downstream processing of recombinant monoclonal antibody
Journal of Chromatography A·2009· 14 cited
2-D DIGE to expedite downstream process development for human monoclonal antibody purification
Protein Expression and Purification·2009· 48 cited
A study of monoclonal antibody‐producing CHO cell lines: What makes a stable high producer?
Biotechnology and Bioengineering·2008· 307 citedOpen Access
Simultaneous determination of 19 intracellular nucleotides and nucleotide sugars in Chinese Hamster ovary cells by capillary electrophoresis
Journal of Chromatography B·2008· 45 cited
The future of biomanufacturing in Singapore
Biotechnology Journal·2007· 1 citedOpen Access
Meeting Report: Second Singapore Biologics Manufacturing Conference
Biotechnology Journal·2007· 2 citedOpen Access
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Frequent Co-authors

Miranda G.S. Yap(12), Dong‐Yup Lee(8), Miranda G.S. Yap(7), Ying Swan Ho(5), Yih Yean Lee(5), Janet Chusainow(4), Poh Choo Toh(4), William P. K. Chong(4), Faraaz N.K. Yusufi(4), Daniel I. C. Wang(4), Franck C. Courtes(4), Danny Wong(3), Satty G. Reddy(3), Chew‐Kiat Heng(3), Julita K. Grzeskowiak(3), Anne Tscheließnig(3), Alois Jungbauer(3), Huatao Feng(3), Yuansheng Yang(2), Lydia Wati(2)