Robert J. Lee

Chongqing Technology and Business University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

75h-index20.4kcitations394works3.42yr avg
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Research Topics

RNA Interference and Gene Delivery(169), Advanced biosensing and bioanalysis techniques(104), Nanoparticle-Based Drug Delivery(97), MicroRNA in disease regulation(32), DNA and Nucleic Acid Chemistry(23)

Publications394 total

Virus-inspired lipopeptide-derived nucleic acid delivery to cartilage for osteoarthritis therapy
Nature Communications·2025· 2 citedOpen Access
Cellular-nanoporation boosts high-yield RVG-modified exosomes for multifunctional α-synuclein scavengers against Parkinson's disease
Chinese Chemical Letters·2025
Small nucleic acid therapeutics: delivery breakthroughs, clinical translation, and future paradigms in precision medicine
International Journal of Pharmaceutics·2025· 1 cited
Novel potent and selective inhibitors targeting FLT3 for AML therapy.
Journal of Clinical Oncology·2025· 2 cited
ROS-Responsive Biomimetic Nanocomplexes of Liposomes and Macrophage-Derived Exosomes for Combination Breast Cancer Therapy
International Journal of Nanomedicine·2025· 8 citedOpen Access
Harnessing the Potential of Exosomes in Therapeutic Interventions for Brain Disorders
International Journal of Molecular Sciences·2025· 15 citedOpen Access
Decellularized dermis allograft for the treatment of venous leg ulceration: the DAVE RCT
British journal of surgery·2025· 2 citedOpen Access
Jet-milling co-grounds of APIs with polysorbate 80, lecithin and sucrose esters: Particle characteristics and impacts on agglomeration and dissolution efficiency
Advanced Powder Technology·2025· 2 cited
Surface Solid Dispersion of Ketoconazole on Trehalose Dihydrate using Spray Drying to Achieve Enhanced Dissolution Rate
AAPS PharmSciTech·2024· 3 cited
Abstract 3252: Anti-tumor effect of the combination of a lipid nanoparticle suspension of an AKT-1 antisense oligonucleotide (WGI-0301) with tyrosine kinase inhibitors in an orthotopic murine tumor model
Cancer Research·2024
Enhanced dissolution rates of glibenclamide through solid dispersions on microcrystalline cellulose and mannitol, combined with phosphatidylcholine
Drug Development and Industrial Pharmacy·2024· 2 cited
Improved Targeting and Safety of Doxorubicin through a Novel Albumin Binding Prodrug Approach
ACS Omega·2023· 7 citedOpen Access
Abstract A174: Antitumor activity of lipid nanoparticle-delivered anti-miR-21
Molecular Cancer Therapeutics·2023· 1 cited
Abstract B049: Lipid nanoparticle-delivered toll-like receptor agonists are highly effective in cancer immunotherapy
Cancer Immunology Research·2023
Optimized Liposomal Delivery of Bortezomib for Advancing Treatment of Multiple Myeloma
Pharmaceutics·2023· 7 citedOpen Access
Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer
Nature Communications·2023· 52 citedOpen Access
Macrophage-Targeted Lipid Nanoparticle Delivery of microRNA-146a to Mitigate Hemorrhagic Shock-Induced Acute Respiratory Distress Syndrome
ACS Nano·2023· 36 citedOpen Access
Clinical overview of InBrace Generation 2.0.
PubMed·2023· 2 cited
Abstract 701: Evaluation of an AKT-1 antisense oligonucleotide in combination with Lenvatinib and Everolimus in Renca-luciferase syngeneic orthotopic murine tumor model
Cancer Research·2023· 1 cited
Abstract 5123: The anti-tumor and anti-angiogenic effects of a lipid nanoparticle suspension of an AKT-1 anti-sense oligonucleotide
Cancer Research·2023· 2 cited
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Frequent Co-authors

Bo Yu(6), Josimar O. Eloy(4), Wenjin Guo(4), Lesheng Teng(4), Philip S. Low(3), Raquel Petrilli(3), Jing Xie(3), Zhaogang Yang(3), L. James Lee(3), Jun Wu(3), John C. Byrd(3), Michael A. Caligiuri(3), Ramiro Garzon(3), Natarajan Muthusamy(3), Guido Marcucci(3), Werner Tjarks(3), Xinwei Cheng(2), Marina Claro de Souza(2), Juliana Maldonado Marchetti(2), Xiaobin Zhao(2)