William Yang

National Institutes of Health — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index811citations17works0.02yr avg
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Research Topics

DNA Repair Mechanisms(8), T-cell and B-cell Immunology(6), Immune Cell Function and Interaction(5), Insect-Plant Interactions and Control(2), Immunotherapy and Immune Responses(2)

Publications17 total

Promoter Proximity Defines Mutation Window for VH and VΚ Genes Rearranged to Different J Genes
The Journal of Immunology·2022· 4 citedOpen Access
Transcriptome and IgH Repertoire Analyses Show That CD11chi B Cells Are a Distinct Population With Similarity to B Cells Arising in Autoimmunity and Infection
Frontiers in Immunology·2021· 33 citedOpen Access
DNA Breaks in Ig V Regions Are Predominantly Single Stranded and Are Generated by UNG and MSH6 DNA Repair Pathways
The Journal of Immunology·2019· 5 citedOpen Access
DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes
The Journal of Experimental Medicine·2016· 28 citedOpen Access
ATAD5 Deficiency Decreases B Cell Division and <i>Igh</i> Recombination
The Journal of Immunology·2014· 14 citedOpen Access
DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions
The Journal of Experimental Medicine·2012· 45 citedOpen Access
XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in<i>Igh</i>genes
The Journal of Cell Biology·2011
XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in <i>Igh</i> genes
The Journal of Experimental Medicine·2011· 57 citedOpen Access
Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions
Nature Immunology·2010· 130 citedOpen Access
Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase ι
DNA repair·2006· 36 cited
Different mutation signatures in DNA polymerase η- and MSH6-deficient mice suggest separate roles in antibody diversification
Proceedings of the National Academy of Sciences·2005· 120 citedOpen Access
Deoxyuridine Is Generated Preferentially in the Nontranscribed Strand of DNA from Cells Expressing Activation-Induced Cytidine Deaminase
The Journal of Immunology·2005· 23 citedOpen Access
A Role for Msh6 But Not Msh3 in Somatic Hypermutation and Class Switch Recombination
The Journal of Experimental Medicine·2004· 158 citedOpen Access
Absence of DNA Polymerase η Reveals Targeting of C Mutations on the Nontranscribed Strand in Immunoglobulin Switch Regions
The Journal of Experimental Medicine·2004· 70 citedOpen Access
Interaction of<i>Drosophila</i>and Its Endosymbiont<i>Wolbachia:</i>Natural Heat Shock and the Overcoming of Sexual Incompatibility
American Zoologist·1999· 38 citedOpen Access
Overcoming cytoplasmic incompatibility in Drosophila
Proceedings of the Royal Society B Biological Sciences·1998· 50 cited
DNA MISMATCH REPAIR PROTEIN MUTH FROM E. COLI
1997

Frequent Co-authors

Patricia J. Gearhart(14), Robert W. Maul(9), Huseyin Saribasak(6), Stella Martomo(5), Rhonda L. McClure(3), Roger Woodgate(3), David M. Wilson(3), Zheng Cao(3), Alexandra Vaisman(2), Masayuki Yokoi(2), Fumio Hanaoka(2), Daniel R. McNeill(2), Timothy L. Karr(2), Kimberly J. Zanotti(2), H. Gramlich(1), David G. Schatz(1), Robert P. Wersto(1), Tsuyoshi Ohkumo(1), Yuji Kondo(1), Chikahide Masutani(1)