Vicky C. H. Lai

Regeneron (United States) — United States

Medicine · Health Sciences

14h-index759citations21works0.02yr avg
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Research Topics

Hepatitis C virus research(13), Biochemical and Molecular Research(7), HIV/AIDS drug development and treatment(6), Hepatitis B Virus Studies(5), Animal Virus Infections Studies(5)

Publications21 total

Effects of Blood Processing and Sample Storage on The Stability of Biotherapeutics and Anti-Drug Antibodies
Bioanalysis·2015· 6 cited
Synthesis of pyrrolo[2,3-d]pyrimidine nucleoside derivatives as potential anti-HCV agents
Bioorganic Chemistry·2006· 50 cited
New Superfamily Members Identified for Schiff-Base Enzymes Based on Verification of Catalytically Essential Residues
Biochemistry·2006· 24 cited
The Amino-Terminal Domain of Bovine Viral Diarrhea Virus N<sup>pro</sup>Protein Is Necessary for Alpha/Beta Interferon Antagonism
Journal of Virology·2005· 93 citedOpen Access
Establishment of a Subgenomic Replicon for Bovine Viral Diarrhea Virus in Huh-7 Cells and Modulation of Interferon-Regulated Factor 3-Mediated Antiviral Response
Journal of Virology·2005· 35 citedOpen Access
Replicon Cell Culture System as a Valuable Tool in Antiviral Drug Discovery against Hepatitis C Virus
Antiviral chemistry & chemotherapy·2005· 47 citedOpen Access
Synthesis of 9-(2-β-C-methyl-β-d-ribofuranosyl)-6-substituted purine derivatives as inhibitors of HCV RNA replication
Bioorganic & Medicinal Chemistry Letters·2004· 28 cited
Parallel synthesis of pteridine derivatives as potent inhibitors for hepatitis C virus NS5B RNA-dependent RNA polymerase
Bioorganic & Medicinal Chemistry Letters·2004· 34 citedOpen Access
Synthesis of New 2′‐β‐C‐Methyl Related Triciribine Analogues as anti‐HCV Agents.
ChemInform·2004
Synthesis of new 2′-β-C-methyl related triciribine analogues as anti-HCV agents
Bioorganic & Medicinal Chemistry Letters·2004· 14 cited
&lt;I&gt;In Situ&lt;/I&gt; Hybridization for the Detection and Localization of HBV DNA in Liver Sections
Humana Press eBooks·2004· 2 cited
Canonical 3′-deoxyribonucleotides as a chain terminator for HCV NS5B RNA-dependent RNA polymerase
Antiviral Research·2003· 49 cited
In Vitro RNA Replication Directed by Replicase Complexes Isolated from the Subgenomic Replicon Cells of Hepatitis C Virus
Journal of Virology·2003· 60 citedOpen Access
Comparative Analysis of Anti-Hepatitis C Virus Activity and Gene Expression Mediated by Alpha, Beta, and Gamma Interferons
Journal of Virology·2002· 79 citedOpen Access
Mutations in NS5B Polymerase of Hepatitis C Virus: Impacts on in Vitro Enzymatic Activity and Viral RNA Replication in the Subgenomic Replicon Cell Culture
Virology·2002· 50 cited
Characterization of monoclonal antibodies that specifically recognize the palm subdomain of hepatitis C virus nonstructural protein 5B polymerase
Virus Research·2001· 6 cited
Failure to identify specific sequence variations in genotype 1b HCV NS58 associated with response to interferon/ribavirin therapy
Gastroenterology·2001· 1 cited
Generation and Characterization of a Hepatitis C Virus NS3 Protease-Dependent Bovine Viral Diarrhea Virus
Journal of Virology·2000· 36 citedOpen Access
Mutational Analysis of Bovine Viral Diarrhea Virus RNA-Dependent RNA Polymerase
Journal of Virology·1999· 107 citedOpen Access
Nucleic Acid-Based Cross-Linking Assay for Detection and Quantification of Hepatitis B Virus DNA
Journal of Clinical Microbiology·1999· 30 citedOpen Access
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Frequent Co-authors

Weidong Zhong(14), Zhi Hong(9), Johnson Y. N. Lau(5), Jean‐Luc Girardet(5), Shannon Dempsey(4), Haoyun An(4), Zhi Hong(4), Yili Ding(4), Rubén O. Donis(3), Nigel Horscroft(3), Esmir Gunić(3), Jim Zhen Wu(3), Kenneth L. Smith(3), Brett J. Prigaro(3), Israr-ul H. Ansari(2), Delin Liang(2), I. Wayne Cheney(2), Suhaila Naim(2), Nanhua Yao(2), Paul Ingravallo(2)