Hsiang‐Ting Lei

Howard Hughes Medical Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index774citations26works0.02yr avg
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Research Topics

Antibiotic Resistance in Bacteria(7), Amino Acid Enzymes and Metabolism(6), RNA and protein synthesis mechanisms(5), Cellular transport and secretion(4), Chemical Synthesis and Analysis(4)

Publications26 total

Lipid flipping in the omega-3 fatty-acid transporter
Nature Communications·2023· 32 citedOpen Access
Lipid translocation in the omega-3 fatty-acid transporter MFSD2A
Biophysical Journal·2023Open Access
Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3
Journal of Medicinal Chemistry·2022· 18 citedOpen Access
Lipid flipping in the omega-3 fatty-acid transporter
2022· 2 citedOpen Access
A conformational change in the N terminus of SLC38A9 signals mTORC1 activation
Structure·2020· 28 citedOpen Access
Structural basis for substrate binding and specificity of a sodium–alanine symporter AgcS
Proceedings of the National Academy of Sciences·2019· 20 citedOpen Access
A conformational change in the N terminus of SLC38A9 signals mTORC1 activation
2018· 1 citedOpen Access
Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state
Nature Structural & Molecular Biology·2018· 63 citedOpen Access
Structural basis for substrate binding and specificity of a sodium/alanine symporter AgcS
2018Open Access
Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state
2018· 1 citedOpen Access
Crystal structure of sodium/alanine symporter AgcS with L-alanine bound
2018· 13 cited
Zebrafish SLC38A9 with arginine bound in the cytosol open state
2017
Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump
Nature Communications·2017· 83 citedOpen Access
Crystal structure of the <i>Mycobacterium tuberculosis</i> transcriptional regulator Rv0302
Protein Science·2015· 13 citedOpen Access
Crystal Structure of the Open State of the Neisseria gonorrhoeae MtrE Outer Membrane Channel
PLoS ONE·2014· 84 citedOpen Access
Crystal Structure of the Neisseria gonorrhoeae MtrD Inner Membrane Multidrug Efflux Pump
PLoS ONE·2014· 79 citedOpen Access
Crystal structure of the <i>Campylobacter jejuni</i> CmeC outer membrane channel
Protein Science·2014· 33 citedOpen Access
Crystal structure of the transcriptional regulator Rv1219c of <i>Mycobacterium tuberculosis</i>
Protein Science·2014· 35 citedOpen Access
Characterization of bacterial RND efflux systems via transcriptional regulator CmeR and outer membrane channels CusC and MtrE
2014Open Access
Crystal Structures of CusC Review Conformational Changes Accompanying Folding and Transmembrane Channel Formation
Journal of Molecular Biology·2013· 39 cited
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Frequent Co-authors

Chih‐Chia Su(11), Edward Yu(11), Jani Reddy Bolla(10), Tamir Gonen(10), Kanagalaghatta R. Rajashankar(8), Tsung‐Han Chou(6), Nitin Kumar(6), Abhijith Radhakrishnan(6), Feng Long(6), Victor L. Sylvia(6), Jared A. Delmar(5), Jinming Ma(5), Qijing Zhang(4), Louis Tung Faat Lai(3), Xuelang Mu(3), Doreen Matthies(3), F.E. Reyes(3), William M. Shafer(2), Lei Dai(2), Catherine C. Wright(2)