Rebecca Upton

University of Liverpool — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index943citations24works0.02yr avg
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Research Topics

Adenosine and Purinergic Signaling(9), Receptor Mechanisms and Signaling(6), Synthesis and Biological Evaluation(5), Neuroscience and Neuropharmacology Research(4), Pharmacological Receptor Mechanisms and Effects(4)

Publications23 total

558 PREVALENCE AND IMPACT OF FRAILTY IN PATIENTS HOSPITALISED WITH COVID-19. THE SALFORD EXPERIENCE IN WAVES 1 AND 2
Age and Ageing·2021Open Access
466 PREVALENCE AND IMPACT OF FRAILTY IN PATIENTS HOSPITALISED WITH COVID-19. THE SALFORD EXPERIENCE IN WAVES 1 AND 2
Age and Ageing·2021· 1 citedOpen Access
Perceptions of Infertility as a Barrier to Cervical Cancer Screening in Rural Botswana: A Qualitative Study
Journal of Community Medicine & Health Education·2018· 2 citedOpen Access
Nurses as Mediators in the Madagascar Healthcare System
2016
Antagonists of the Human A<sub>2A</sub> Adenosine Receptor. 4. Design, Synthesis, and Preclinical Evaluation of 7-Aryltriazolo[4,5-<i>d</i>]pyrimidines
Journal of Medicinal Chemistry·2008· 103 citedOpen Access
Antagonists of the human adenosine A2A receptor. Part 2: Design and synthesis of 4-arylthieno[3,2-d]pyrimidine derivatives
Bioorganic & Medicinal Chemistry Letters·2008· 32 citedOpen Access
Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives
Bioorganic & Medicinal Chemistry Letters·2008· 48 citedOpen Access
Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines
Bioorganic & Medicinal Chemistry Letters·2008· 65 citedOpen Access
Lung heme oxygenase-1 is elevated in acute respiratory distress syndrome
Critical Care Medicine·2004· 100 cited
Novel purine derivatives as selective adenosine A(2A) receptor antagonists for the treatment of Parkinson's disease.
Abstracts of papers - American Chemical Society·2004
Synthesis and evaluation of novel pyrazolo[3,4-d] pyrimidine derivatives as selective adenosine A(2A) receptor antagonists.
Abstracts of papers - American Chemical Society·2004
Synthesis and SAR of novel thieno[3,2-d]pyrimidine derivatives as selective antagonists of the adenosine A(2A) receptor.
Abstracts of papers - American Chemical Society·2004
Discovery of nonxanthine adenosine A 2A receptor antagonists for the treatment of Parkinson's disease
2003· 11 cited
Discovery of nonxanthine adenosine A<sub>2A</sub>receptor antagonists for the treatment of Parkinson’s disease
Neurology·2003· 77 cited
Potential for antipsychotic and psychotomimetic effects of A<sub>2A</sub>receptor modulation
Neurology·2003· 16 cited
Variable tissue expression of transferrin receptors: relevance to acute respiratory distress syndrome
European Respiratory Journal·2003· 25 citedOpen Access
The Muscarinic Receptor Agonist Xanomeline Has an Antipsychotic-Like Profile in the Rat
Journal of Pharmacology and Experimental Therapeutics·2001· 129 cited
"Our blood does not agree" : negotiating infertility in Northern Botswana
Medical Entomology and Zoology·1999· 5 cited
Increased extracellular dopamine in the nucleus accumbens of the rat during associative learning of neutral stimuli
Neuroscience·1998· 153 cited
l -2-Chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists
Archives of Toxicology·1997· 2 cited
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Frequent Co-authors

Scott Μ. Weiss(11), Joanne Lerpiniere(9), Colin T. Dourish(9), Ian A. Cliffe(8), Suneel Gaur(7), Robert M. Pratt(7), Karen Benwell(6), R. J. Gillespie(5), Claire Dawson(5), Roger J. Gillespie(4), Allan M. Jordan(4), Anil Kumar Misra(4), Gemma C. Stratton(4), Anthony J. Lawrence(4), Richard S. Todd(3), Aditya Misra(3), Antony R. Knight(3), D.S. Williamson(3), Paul R. Giles(3), Andrew Gyte(3)