Philipp Bücher

SIB Swiss Institute of Bioinformatics — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

54h-index13.0kcitations147works4.02yr avg
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Research Topics

Genomics and Chromatin Dynamics(56), RNA and protein synthesis mechanisms(48), Genomics and Phylogenetic Studies(35), RNA Research and Splicing(23), RNA modifications and cancer(16)

Publications147 total

Inferring binding specificities of human transcription factors with the wisdom of crowds
2025Open Access
Cross-platform motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors
Communications Biology·2025· 3 citedOpen Access
Codebook Motif Explorer Supplementary Dataset
Zenodo (CERN European Organization for Nuclear Research)·2025· 2 citedOpen Access
Extensive binding of nebulous human transcription factors to genomic dark matter
2024· 10 citedOpen Access
Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors
2024· 1 citedOpen Access
Perspectives on Codebook: sequence specificity of uncharacterized human transcription factors
2024· 7 citedOpen Access
ElemeNT 2023: an enhanced tool for detection and curation of core promoter elements
Bioinformatics·2024· 5 citedOpen Access
Codebook Motif Explorer Supplementary Dataset
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Codebook Motif Explorer Supplementary Dataset
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Computational identification and experimental characterization of preferred downstream positions in human core promoters
PLoS Computational Biology·2021· 4 citedOpen Access
Abstract 2993: Intraductal xenografts model ERα-positive invasive lobular carcinoma of the breast
Cancer Research·2021Open Access
Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation
EMBO Molecular Medicine·2021· 40 citedOpen Access
Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1
EMBO Molecular Medicine·2021· 50 citedOpen Access
Computational identification and experimental characterization of preferred downstream positions in human core promoters
2021· 3 citedOpen Access
Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study
Genome biology·2020· 76 citedOpen Access
The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche
Nature Communications·2020· 56 citedOpen Access
Data for the paper "Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study".
2020· 1 citedOpen Access
Data for the paper "Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study".
Zenodo (CERN European Organization for Nuclear Research)·2020Open Access
Additional file 3 of Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study
Figshare·2020Open Access
Additional file 2 of Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study
Figshare·2020Open Access
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Frequent Co-authors

Giovanna Ambrosini(11), C. Victor Jongeneel(8), Kay Hofmann(7), Christian Iseli(5), René Dreos(5), Romain Groux(5), Markus Nabholz(4), Patrick Reichenbach(3), Christoph D. Schmid(3), Walter Reith(3), Stephen F. Altschul(2), Volker Brendel(2), Samuel Karlin(2), Didier Trono(2), R Périer(2), Emmanouil T. Dermitzakis(2), Alexandre Reymond(2), Brian J. Stevenson(2), Stylianos E. Antonarakis(2), Sunil Kumar(2)