Nigel J. Parr

Wirral University Teaching Hospital NHS Foundation Trust — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index2.4kcitations73works1.52yr avg
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Research Topics

Protein Degradation and Inhibitors(18), Prostate Cancer Treatment and Research(13), Multiple Myeloma Research and Treatments(13), Prostate Cancer Diagnosis and Treatment(10), Bone health and treatments(9)

Publications73 total

Synchronous Insertion of Hyaluronic Acid-Based Biodegradable Rectal Spacer for Primary Prostate Cryotherapy
JU Open Plus·2024· 2 citedOpen Access
Image intensifier‐guided transperineal prostate biopsy for patients without a rectum: novel technique
British Journal of Urology·2024· 1 cited
Supplemental Figures S1-S6 from Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
2023Open Access
Supplemental Methods and References from Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
2023Open Access
Data from Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
2023Open Access
Supplementary Tables S1-S8 from Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
2023Open Access
Data from Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
2023Open Access
Supplementary Tables S1-S8 from Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
2023Open Access
Supplemental Figures S1-S6 from Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
2023Open Access
Supplemental Methods and References from Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
2023Open Access
Phase 1 and preclinical profiling of ESM‐HDAC391, a myeloid‐targeted histone deacetylase inhibitor, shows enhanced pharmacology and monocytopaenia
British Journal of Clinical Pharmacology·2022· 4 citedOpen Access
Phase 1 and pre-clinical profiling of ESM-HDAC391, a myeloid-targeted histone deacetylase inhibitor, shows enhanced pharmacology and monocytopaenia
2022Open Access
Discovery of a Novel Bromodomain and Extra Terminal Domain (BET) Protein Inhibitor, I-BET282E, Suitable for Clinical Progression
Journal of Medicinal Chemistry·2021· 39 citedOpen Access
Guidance for the assessment and management of prostate cancer treatment-induced bone loss. A consensus position statement from an expert group
Journal of bone oncology·2020· 65 citedOpen Access
Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors
JNCI Cancer Spectrum·2019· 197 citedOpen Access
Dislodged nephrostomy: a top tip
BMJ Innovations·2018· 1 cited
Active Surveillance Following Modified Transperineal Template Guided Saturation Biopsy Demonstrates a Low Rate of Progression and Conversion to Radical Treatment, with Age and PSA Associated with Upgrading, Upstaging and Treatment
Advances in Cancer Prevention·2017Open Access
Abstract CT014: GSK525762, a selective bromodomain (BRD) and extra terminal protein (BET) inhibitor: results from part 1 of a phase I/II open-label single-agent study in patients with NUT midline carcinoma (NMC) and other cancers
Cancer Research·2016· 37 cited
Contents Vol. 96, 2016
Urologia Internationalis·2016Open Access
Patient-Reported Experience of Modified Transperineal Template Guided Saturation Biopsy Under General Anaesthesia and without Prophylactic Catheterisation
Urologia Internationalis·2016· 3 cited
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Frequent Co-authors

Rab K. Prinjha(10), Robin Weston(9), Vivek K. Wadhwa(7), Nicholas Smithers(6), Jason Witherington(5), Olena Barbash(5), Leanne Cutler(4), Chun‐wa Chung(4), David F. Tough(4), Kingsley Ekwueme(4), Jan Scicinski(4), Andrea Haynes(3), Katherine L. Jones(3), Anastasia Wyce(3), BaoChau Le(3), Peter J. Tummino(3), Anna K. Bassil(3), Alan C. Spivey(3), Christopher J. G. Gripton(3), Maurice Lau(3)