Amy C. Anderson

University of Connecticut — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

34h-index4.0kcitations114works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Biochemical and Molecular Research(24), Click Chemistry and Applications(18), Pneumocystis jirovecii pneumonia detection and treatment(17), Enzyme Structure and Function(16), HIV/AIDS drug development and treatment(12)

Publications114 total

Complicated Infective Endocarditis Due to Methicillin-Sensitive Staphylococcus aureus and Streptococcus canis Bacteremia: A Multisystem Case Requiring Interdisciplinary Management
Cureus·2025Open Access
Comparative pharmacokinetics of seven propargyl-linked antifolate antibiotics in the mouse
Journal of Chromatography B·2025
Safety and efficacy of proton beam therapy in high-risk hepatocellular carcinoma patients previously treated with Yttrium-90 Radioembolization
International Journal of Particle Therapy·2024Open Access
Clinical Outcomes and Immunotoxicity in People with HIV (PWH) after Definitive Chemoradiation (CRT) for Anal Squamous Cell Carcinoma
International Journal of Radiation Oncology*Biology*Physics·2023
Crystal structure of the bacterial cellulose synthase subunit G (BcsG) catalytic domain from Escherichia coli, selenomethionine variant
2019
Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens
Biochemistry·2019· 33 cited
Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse
Journal of Chromatography B·2017· 2 citedOpen Access
Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks
Organic Letters·2016· 3 citedOpen Access
OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design
Methods in molecular biology·2016· 18 citedOpen Access
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates
Cell chemical biology·2016· 31 citedOpen Access
Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis
Pharmacological Research·2016· 22 citedOpen Access
Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis
PLoS ONE·2016· 28 citedOpen Access
Antibacterial Antifolates: From Development through Resistance to the Next Generation
Cold Spring Harbor Perspectives in Medicine·2016· 76 citedOpen Access
Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations
Journal of Medicinal Chemistry·2016· 31 citedOpen Access
Crystal structures of the resistance-conferring dfrA1 reveal that propargyl-linked antifolates are potent inhibitors
ACS Infectious Diseases·2016
Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens
ACS Medicinal Chemistry Letters·2016· 36 citedOpen Access
Staphylococcus aureus Dihydrofolate Reductase complexed with beta-NADPH, cyclic alpha-NADPH anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (UCP1106)
2016
Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates
ACS Infectious Diseases·2015· 42 citedOpen Access
The Challenge of Resistance in Antimicrobial Drug Development
Future Microbiology·2015· 2 citedOpen Access
Understanding the Structural Mechanisms of Antibiotic Resistance Sets the Platform for New Discovery
Future Microbiology·2015· 16 citedOpen Access
page 1 of 6Next →

Frequent Co-authors

Dennis L. Wright(29), Kathleen M. Frey(8), Bruce R. Donald(7), Michael N. Lombardo(7), Stephanie M. Reeve(6), Santosh Keshipeddy(6), Nigel D. Priestley(6), Eric W. Scocchera(6), Ivelin S. Georgiev(5), Erin S. D. Bolstad(5), David B. Bolstad(5), Narendran G-Dayanandan(5), Ryan Lilien(4), Jeremy B. Alverson(4), Wangda Zhou(3), Robert H. O’Neil(3), Robert M. Stroud(3), Veljko M. Popov(3), Jennifer M. Beierlein(3), Jieying Liu(3)