Charles L. Brooks

University of Michigan — United States

Medicine · Health Sciences

32h-index4.1kcitations108works0.52yr avg
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Research Topics

Growth Hormone and Insulin-like Growth Factors(24), Protein Structure and Dynamics(17), Enzyme Structure and Function(12), Metabolism, Diabetes, and Cancer(10), Estrogen and related hormone effects(7)

Publications108 total

Core Flipping in Lead Optimization: Rank Ordering using Multisite λ Dynamics
2024Open Access
Core Flipping in Lead Optimization: Rank Ordering using Multisite λ Dynamics
2024· 1 citedOpen Access
VIPERdb v3.0: a structure-based data analytics platform for viral capsids
Nucleic Acids Research·2020· 77 citedOpen Access
Enjoying sad music: A test of the prolactin theory
Musicae Scientiae·2019· 41 cited
Structural Basis for Selectivity in Flavin-Dependent Monooxygenase-Catalyzed Oxidative Dearomatization
2018Open Access
Protein Phosphorylation of Prolactin Target Tissue: Mammary Gland
2018
Tuning RNA folding and function through rational design of junction topology
Nucleic Acids Research·2017· 11 citedOpen Access
Editorial
Protein Science·2015Open Access
Enhanced Sampling Assisted Flexible Fitting of Atomic Structures into Electron Microscopy Maps
Biophysical Journal·2013Open Access
Molecular Simulations of pH-Dependant Maturation-Associated Structural Changes in Bacteriophage HK97
Biophysical Journal·2013Open Access
Molecular Mechanisms of Prolactin and Its Receptor
Endocrine Reviews·2012· 164 citedOpen Access
The High Dielectric Constant of Staphylococcal Nuclease Is Encoded in Its Structural Architecture
Journal of the American Chemical Society·2011· 15 citedOpen Access
A nine-base nucleotide sequence in the porcine circovirus type 2 (PCV2) nucleocapsid gene determines viral replication and virulence
Virus Research·2011· 39 cited
Functional Impact of Manipulation in Relative Orientation of Human Prolactin Receptor Domains
2011Open Access
Significance of Intermolecular Disulfide Linkage in Human Prolactin Receptor Ligand-Independent Dimerization and Ligand-Induced Activation
2011
Functional Impact of Manipulation on the Relative Orientation of Human Prolactin Receptor Domains
Biochemistry·2011· 13 cited
Zinc binding to human lactogenic hormones and the human prolactin receptor
FEBS Letters·2011· 9 citedOpen Access
Functional Epitopes for Site 1 of Human Prolactin
Biochemistry·2011· 8 cited
Obligate Ordered Binding of Human Lactogenic Cytokines
Journal of Biological Chemistry·2010· 16 citedOpen Access
Functionally Important Conformations of the Met20 Loop in Dihydrofolate Reductase are Populated by Rapid Thermal Fluctuations
Journal of the American Chemical Society·2009· 54 citedOpen Access
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Frequent Co-authors

Lawrence J. Berliner(6), Charles C. Capen(4), Eugene A. Permyakov(4), Francis C. Peterson(3), Patricia J. Anderson(3), John R. Latendresse(3), Serge E. Permyakov(3), Vladimir N. Uversky(3), Dmitry B. Veprintsev(3), Steven Krakowka(2), Mauricio Carrillo‐Tripp(2), Vijay Reddy(2), Brian N. Dominy(2), Jianhan Chen(2), Michael Oglesbee(2), Jerry R. Colca(2), M Landt(2), Michael L. McDaniel(2), Patricia A. Schenck(2), Dennis J. Chew(2)