Suxin Zheng

Computer Science · Physical Sciences

17h-index858citations24works0.02yr avg
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Research Topics

Computational Drug Discovery Methods(4), RNA and protein synthesis mechanisms(4), RNA Research and Splicing(4), Chemical Synthesis and Analysis(3), Toxin Mechanisms and Immunotoxins(3)

Publications24 total

Oral Delivery of Propofol with Methoxymethylphosphonic Acid as the Delivery Vehicle
Journal of Medicinal Chemistry·2017· 59 cited
Discovery of a Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor (HSK0935) for the Treatment of Type 2 Diabetes
Journal of Medicinal Chemistry·2017· 34 citedOpen Access
CCDC 1566466: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
CCDC 1566465: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
Targeted inhibition of oncogenic miR-21 maturation with designed RNA-binding proteins
Nature Chemical Biology·2016· 45 citedOpen Access
Discovery of novel orally bioavailable GPR40 agonists
Bioorganic & Medicinal Chemistry Letters·2013· 12 citedOpen Access
The structure of a <i>Burkholderia pseudomallei</i> immunophilin–inhibitor complex reveals new approaches to antimicrobial development
Biochemical Journal·2011· 21 citedOpen Access
Fragment‐based discovery of novel thymidylate synthase leads by NMR screening and group epitope mapping
Chemical Biology & Drug Design·2010· 17 citedOpen Access
Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with 1-{[(4-methylphenyl)thio]acetyl}piperidine. Seattle Structure Genomics Center for Infectious Disease (SSGCID)
Journal of Back and Musculoskeletal Rehabilitation·2010Open Access
Mitoxantrone Analogues as Ligands for a Stem−Loop Structure of Tau Pre-mRNA
Journal of Medicinal Chemistry·2009· 53 citedOpen Access
Structural Basis for Stabilization of the Tau Pre-mRNA Splicing Regulatory Element by Novantrone (Mitoxantrone)
Chemistry & Biology·2009· 94 citedOpen Access
Solution structure of Glutaredoxin from Brucella melitensis. Seattle Structure Genomics Center for Infectious Disease (SSGCID) (Target ID BrabA.00079.a)
Biological Magnetic Resonance Bank·2009Open Access
Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei. Seattle Structure Genomics Center for Infectious Disease (SSGCID)
Biological Magnetic Resonance Bank·2009Open Access
A knowledge‐based potential function predicts the specificity and relative binding energy of RNA‐binding proteins
FEBS Journal·2007· 46 citedOpen Access
Molecular Insight into the Interaction between IFABP and PA by Using MM−PBSA and Alanine Scanning Methods
The Journal of Physical Chemistry B·2007· 20 cited
Discovering Potassium Channel Blockers from Synthetic Compound Database by Using Structure-Based Virtual Screening in Conjunction with Electrophysiological Assay
Journal of Medicinal Chemistry·2006· 32 citedOpen Access
Study on dual-site inhibitors of acetylcholinesterase: Highly potent derivatives of bis- and bifunctional huperzine B
Bioorganic & Medicinal Chemistry·2006· 39 citedOpen Access
Structural insights into the effect of isonucleosides on B-DNA duplexes using molecular-dynamics simulations
Journal of Molecular Modeling·2006· 7 citedOpen Access
A New Rapid and Effective Chemistry Space Filter in Recognizing a Druglike Database
Journal of Chemical Information and Modeling·2005· 72 cited
Computational analysis of molecular basis of 1:1 interactions of NRG‐1β wild‐type and variants with ErbB3 and ErbB4
Proteins Structure Function and Bioinformatics·2005· 23 cited
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Frequent Co-authors

Hualiang Jiang(10), Gabriele Varani(9), Xiaomin Luo(7), Jianhua Shen(6), Kaixian Chen(6), Cheng Luo(4), Weiliang Zhu(4), Donglu Bai(3), Yonggang Wei(3), Guanpeng Qiu(3), Bai‐Lin Lei(3), Linlin Qin(3), Hongzhu Chu(3), Guozhi Zhu(3), Qingping Huang(3), Guofei Qian(3), Pengfei Liao(3), Xinfeng Luo(3), Pingming Tang(3), Pangke Yan(3)