Conrad C. Weihl

Forschungszentrum Jülich — Germany

Medicine · Health Sciences

18h-index14.7kcitations23works0.02yr avg
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Research Topics

Autophagy in Disease and Therapy(22), Endoplasmic Reticulum Stress and Disease(5), Parkinson's Disease Mechanisms and Treatments(4), Cannabis and Cannabinoid Research(3), Muscle Physiology and Disorders(3)

Publications18 total

High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy
Nature Metabolism·2020· 171 citedOpen Access
Regulation of SQSTM1/p62 via UBA domain ubiquitination and its role in disease
Autophagy·2017· 57 citedOpen Access
Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination
Cell Reports·2017· 36 citedOpen Access
Comparisons of ELISA and Western blot assays for detection of autophagy flux
Data in Brief·2017· 14 citedOpen Access
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
Nature Communications·2017· 345 citedOpen Access
Quantification of autophagy flux using LC3 ELISA
Analytical Biochemistry·2017· 51 cited
Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination
Cell Reports·2017· 153 citedOpen Access
<scp>VCP</scp> /p97 cooperates with <scp>YOD</scp> 1, <scp>UBXD</scp> 1 and <scp>PLAA</scp> to drive clearance of ruptured lysosomes by autophagy
The EMBO Journal·2016· 346 citedOpen Access
Autophagic vacuolar pathology in desminopathies
Neuromuscular Disorders·2014· 23 citedOpen Access
Increased autophagy accelerates colchicine-induced muscle toxicity
Autophagy·2013· 43 citedOpen Access
Monitoring Autophagy in the Treatment of Protein Aggregate Diseases: Steps Toward Identifying Autophagic Biomarkers
Neurotherapeutics·2013· 15 citedOpen Access
mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy
Human Molecular Genetics·2012· 64 citedOpen Access
Valosin Containing Protein Associated Fronto-Temporal Lobar Degeneration:Clinical Presentation, Pathologic Features and Pathogenesis
Current Alzheimer Research·2011· 41 cited
Quantitation of "autophagic flux" in mature skeletal muscle
Autophagy·2010· 216 citedOpen Access
Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters
Autophagy·2010· 4 cited
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
The Journal of Cell Biology·2009· 484 citedOpen Access
Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters
Autophagy·2009· 46 citedOpen Access
Impaired Protein Aggregate Handling and Clearance Underlie the Pathogenesis of p97/VCP-associated Disease
Journal of Biological Chemistry·2008· 146 citedOpen Access

Frequent Co-authors

Jeong-Sun Ju(9), Sara Miller(5), Sara K. Pittman(5), Babak Razani(4), Erin Jackson(3), Youjin Lee(3), Robert H. Baloh(2), Ismail Sergin(2), Trent D. Evans(2), Xiangyu Zhang(2), Eric Song(2), Karyn B. Holloway(2), Jan R. Crowley(2), Joel D. Schilling(2), Slava Epelman(2), Abhinav Diwan(2), Daping Fan(2), Tsui‐Fen Chou(2), Amy L. Keith(2), James Kain Ching(2)