María Dolores López‐Maderuelo

Spanish National Centre for Cardiovascular Research — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index342citations7works0.02yr avg
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Research Topics

Signaling Pathways in Disease(5), Peptidase Inhibition and Analysis(2), Cardiac Structural Anomalies and Repair(2), Protein Structure and Dynamics(1), Computational Drug Discovery Methods(1)

Publications7 total

Cardiomyocyte calcineurin is required for the onset and progression of cardiac hypertrophy and fibrosis in adult mice
FEBS Journal·2018· 18 citedOpen Access
Inactivation of Nuclear Factor-Y Inhibits Vascular Smooth Muscle Cell Proliferation and Neointima Formation
Arteriosclerosis Thrombosis and Vascular Biology·2013· 20 citedOpen Access
The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators
Proceedings of the National Academy of Sciences·2009· 52 citedOpen Access
A Conserved Docking Surface on Calcineurin Mediates Interaction with Substrates and Immunosuppressants
Molecular Cell·2009· 119 citedOpen Access
Blockade of NFAT Activation by the Second Calcineurin Binding Site
Journal of Biological Chemistry·2006· 68 citedOpen Access
The Linker Region Joining the Catalytic and the Regulatory Domains of CnA Is Essential for Binding to NFAT
Journal of Biological Chemistry·2005· 25 citedOpen Access
Opposite effects of the Hsp90 inhibitor Geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells
FEBS Letters·2001· 40 citedOpen Access

Frequent Co-authors

Juan Miguel Redondo(6), Sara Martínez‐Martínez(5), Antonio Rodrı́guez(4), Inmaculada Ortega‐Pérez(2), Jagoree Roy(1), Perla Niño-Moreno(1), Leticia Ortí(1), David Pantoja‐Uceda(1), Antonio Pineda‐Lucena(1), Martha Cyert(1), Jesús Vázquez(1), Eulàlia Genescà(1), Alicia Raya(1), Eulàlia Salichs(1), Felipe Were(1), Susana de la Luna(1), Margarita Fernández-Renart(1), Carmen Moratilla(1), Jaime Renart(1), Carlos Silvestre-Roig(1)