Peter F. Searle

University of Birmingham — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index4.7kcitations99works0.02yr avg
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Research Topics

Virus-based gene therapy research(46), Cancer Research and Treatments(29), CAR-T cell therapy research(25), RNA Interference and Gene Delivery(13), Viral-associated cancers and disorders(11)

Publications99 total

Data from Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus–Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma
2023Open Access
Supplementary Figure S1 from Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus–Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma
2023Open Access
Supplementary Figure S2 from Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus–Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma
2023Open Access
Supplementary Figure S3 from Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus–Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma
2023Open Access
Supplementary Figure S3 from Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus–Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma
2023Open Access
Supplementary Figure S2 from Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus–Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma
2023Open Access
Data from Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus–Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma
2023Open Access
Supplementary Figure S1 from Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus–Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma
2023Open Access
Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954
International Journal of Molecular Sciences·2023· 3 citedOpen Access
An astronomical fabry-perot spectrometer.
UTAS Research Repository·2023Open Access
Oxygen‐insensitive nitroreductase <i>E. coli</i> <scp>NfsA</scp> , but not <scp>NfsB</scp> , is inhibited by fumarate
Proteins Structure Function and Bioinformatics·2022· 8 citedOpen Access
Author response for "Oxygen‐Insensitive Nitroreductase &lt;i&gt;E. coli&lt;/i&gt; NfsA, but not NfsB, is inhibited by fumarate"
2022
Author response for "Oxygen‐Insensitive Nitroreductase &lt;i&gt;E. coli&lt;/i&gt; NfsA, but not NfsB, is inhibited by fumarate"
2022
The <scp>3D</scp>‐structure, kinetics and dynamics of the <i>E. coli</i> nitroreductase <scp>NfsA</scp> with <scp>NADP</scp><sup>+</sup> provide glimpses of its catalytic mechanism
FEBS Letters·2022· 15 citedOpen Access
The structures of <i>E. coli</i> NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN
Biochemical Journal·2021· 27 citedOpen Access
How not to run out of oxygen: Primary FRCA forcibly put into practice by COVID-19 to maintain patient safety
Journal of Patient Safety and Risk Management·2021· 2 cited
EXTH-44. DEVELOPMENT OF RETROVIRAL REPLICATING VECTORS ENCODING SEQUENCE-OPTIMIZED NITROREDUCTASE FOR PRODRUG ACTIVATOR GENE THERAPY IN HUMAN GLIOMA MODELS
Neuro-Oncology·2020Open Access
433. Sequence-Optimized Nitroreductase for Retroviral Replicating Vector (RRV) Mediated Prodrug Activator Gene Therapy in Human Glioma Models
Molecular Therapy·2015Open Access
Human Leukocyte Antigen (HLA) A*1101-Restricted Epstein-Barr Virus–Specific T-cell Receptor Gene Transfer to Target Nasopharyngeal Carcinoma
Cancer Immunology Research·2015· 35 citedOpen Access
ET-13 * RETROVIRAL REPLICATING VECTOR (RRV)-MEDIATED PRODRUG ACTIVATOR GENE THERAPY WITH CODON-OPTIMIZED NITROREDUCTASE IN EXPERIMENTAL GLIOMA
Neuro-Oncology·2014Open Access
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Frequent Co-authors

Lawrence S. Young(12), Eva I. Hyde(9), Gary W. Stuart(7), Scott A. White(7), Rachel Kerr(7), Vivien Mautner(6), Richard D. Palmiter(5), Paul R. Race(5), Andrew L. Lovering(5), Christopher J. Wrighton(5), Andrew Mountain(5), Longqin Hu(5), Jane I. Grove(4), Christopher P. Guise(4), Mansooreh Jaberipour(4), Simon O. Vass(4), Richard J. Knox(4), Nicholas D. James(3), Nicola K. Green(3), Peter A. Harris(3)