Xiaochu Ma

Micropharma (Canada) — Canada

Immunology and Microbiology · Life Sciences

16h-index2.5kcitations48works0.02yr avg
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Research Topics

HIV Research and Treatment(19), HIV/AIDS drug development and treatment(13), Synthetic Organic Chemistry Methods(9), Cyclopropane Reaction Mechanisms(9), Monoclonal and Polyclonal Antibodies Research(7)

Publications48 total

Abstract 1808: Discovery of highly selective novel MTA-cooperative PRMT5 inhibitors for the treatment of cancers
Cancer Research·2024
Abstract 3943: Discovery of a novel menin-MLL inhibitor for potential treatment of MLLr leukemias and NPM1c AML
Cancer Research·2022
Correction for Lu et al., “Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands”
Journal of Virology·2020· 6 citedOpen Access
Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands
Journal of Virology·2020· 41 citedOpen Access
Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET
Nature·2019· 208 cited
Illuminating the virus life cycle with single-molecule FRET imaging
Advances in virus research·2019· 14 citedOpen Access
Miniaturized whole-cell bacterial bioreporter assay for identification of quorum sensing interfering compounds
Journal of Microbiological Methods·2018· 9 citedOpen Access
Quorum sensing molecules regulate epithelial cytokine response and biofilm-related virulence of three Prevotella species
Anaerobe·2018· 24 cited
Evidence of link between quorum sensing and sugar metabolism in <i>Escherichia coli</i> revealed via cocrystal structures of LsrK and HPr
Science Advances·2018· 111 citedOpen Access
P-C4 Associating HIV-1 Env trimer structures with functional Env conformational states by smFRET analysis
JAIDS Journal of Acquired Immune Deficiency Syndromes·2018· 1 cited
HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations
eLife·2018· 163 citedOpen Access
Author response: HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations
2018Open Access
Single-Molecule FRET Reveals an Additional Conformational State of HIV-1 Envelope Glycoprotein Critical for Vaccine Design
Biophysical Journal·2018Open Access
Publisher Correction: The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions
Nature Communications·2018· 4 citedOpen Access
ALKYNYL AMINOISOQUINOLINES, NOVEL FLT3 KINASE INHIBITORS WITH POTENT ACTIVITY AGAINST ACUTE MYELOID LEUKEMIA
Digital Repository at the University of Maryland (University of Maryland College Park)·2018Open Access
CCDC 1562216: Experimental Crystal Structure Determination
The Cambridge Structural Database·2018Open Access
A triple-functionalised metal centre-catalyzed enantioselective multicomponent reaction
Organic Chemistry Frontiers·2018· 15 cited
The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions
Nature Communications·2017· 111 citedOpen Access
Dipeptidyl peptidase IV and quorum sensing signaling in biofilm-related virulence of Prevotella aurantiaca
Anaerobe·2017· 11 cited
Conformational Changes in HIV-1 Env Trimer Induced by a Single CD4 as Revealed by Cryo-EM
Microscopy and Microanalysis·2017Open Access
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Frequent Co-authors

Walther Mothes(18), Scott C. Blanchard(16), Shunying Liu(15), Wenhao Hu(15), Peter D. Kwong(13), James B. Munro(11), Jason Gorman(11), Maolin Lu(10), Jun Jiang(10), Herman O. Sintim(9), James Arthos(8), Amos B. Smith(8), Daniel S. Terry(8), Joseph Sodroski(8), Fengping Lv(6), Zhou Zhou(5), Xiang Wu(5), Tongqing Zhou(4), Marie Pancera(4), Nick Reichard(4)