Mauricio Vergara

Pontificia Universidad Católica de Valparaíso — Chile

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index438citations29works0.02yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(15), Protein purification and stability(9), Virus-based gene therapy research(7), thermodynamics and calorimetric analyses(3), Acute Ischemic Stroke Management(2)

Publications29 total

One-Pot Enzymatic Bioconversion of Native Whey for the Simultaneous Production of Galacto-Oligosaccharides and Antioxidant Peptides
Foods·2026Open Access
Engineering of Chinese hamster ovary cells for co-overexpressing MYC and XBP1s increased cell proliferation and recombinant EPO production
Scientific Reports·2023· 20 citedOpen Access
Enhanced recombinant protein production in CHO cell continuous cultures under growth-inhibiting conditions is associated with an arrested cell cycle in G1/G0 phase
PLoS ONE·2022· 23 citedOpen Access
Dynamic Culture of Mesenchymal Stromal/Stem Cell Spheroids and Secretion of Paracrine Factors
Frontiers in Bioengineering and Biotechnology·2022· 48 citedOpen Access
Creatividad en la Pyme y efectos sobre la innovación y el desempeño empresarial en una economía emergente
2020· 2 citedOpen Access
Metabolic flux analysis during galactose and lactate co-consumption reveals enhanced energy metabolism in continuous CHO cell cultures
Chemical Engineering Science·2019· 14 citedOpen Access
High glucose and low specific cell growth but not mild hypothermia improve specific r-protein productivity in chemostat culture of CHO cells
PLoS ONE·2018· 32 citedOpen Access
Mild hypothermia upregulates myc and xbp1s expression and improves anti-TNFα production in CHO cells
PLoS ONE·2018· 38 citedOpen Access
Impact of sodium butyrate and mild hypothermia on metabolic and physiological behaviour of CHO TF 70R cells
Electronic Journal of Biotechnology·2017· 25 citedOpen Access
Application of a new model based on oxygen balance to determine the oxygen uptake rate in mammalian cell chemostat cultures
Chemical Engineering Science·2016· 7 cited
Plan de Uso Público Parque Provincial Ischigualasto -Provincia de San Juan-
2016
The Histogram and Relative Breast Density in Mammography
Radiology·2016· 1 cited
Endoplasmic Reticulum-Associated rht-PA Processing in CHO Cells: Influence of Mild Hypothermia and Specific Growth Rates in Batch and Chemostat Cultures
PLoS ONE·2015· 12 citedOpen Access
Antiproliferative evaluation of tall-oil docosanol and tetracosanol over CHO-K1 and human melanoma cells
Electronic Journal of Biotechnology·2015· 21 citedOpen Access
5.3 Nutrient Media for Cell Culture Technology
2014
Characterization of pressurized hot water extracts of grape pomace: Chemical and biological antioxidant activity
Food Chemistry·2014· 59 cited
Differential Effect of Culture Temperature and Specific Growth Rate on CHO Cell Behavior in Chemostat Culture
PLoS ONE·2014· 61 citedOpen Access
Protein folding and glycosylation process are influenced by mild hypothermia in batch culture and by specific growth rate in continuous cultures of CHO cells producing rht-PA
BMC Proceedings·2013· 1 citedOpen Access
Advances in improving mammalian cells metabolism for recombinant protein production
Electronic Journal of Biotechnology·2013· 60 citedOpen Access
Simultaneous environmental manipulations in semi-perfusion cultures of CHO cells producing rh-tPA
Electronic Journal of Biotechnology·2012· 6 citedOpen Access
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Frequent Co-authors

Claudia Altamirano(19), Julio Berríos(16), Juan G. Reyes(8), Silvana Becerra(7), Cristián Acevedo(6), Mauro Torres(5), Nelson Osses(4), Ramón González(4), Verónica Avello(3), Alan J. Dickson(3), Alvaro Díaz‐Barrera(3), Norma A. Valdez‐Cruz(2), Maria Molina Sampayo(2), Claudia Altamirano(2), Yesenia Latorre(2), María Rodríguez‐Moyá(1), José Rodrigo Vergara‐Salinas(1), Á. González(1), José Ricardo Pérez‐Correa(1), Paloma Fuentes(1)