Susanne MacLean

Medicine · Health Sciences

10h-index595citations17works5.02yr avg
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Research Topics

Bone health and treatments(6), CAR-T cell therapy research(5), Protein Kinase Regulation and GTPase Signaling(4), Monoclonal and Polyclonal Antibodies Research(3), T-cell and B-cell Immunology(2)

Publications17 total

Nanobody-Based Multifunctional Killer Engagers for Next-Gen BCMA-Directed Myeloma Therapy
Clinical Lymphoma Myeloma & Leukemia·2025
Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22
Molecular Therapy Oncology·2024· 10 citedOpen Access
Programmable Attenuation of Antigenic Sensitivity for a Nanobody-Based EGFR Chimeric Antigen Receptor Through Hinge Domain Truncation
Frontiers in Immunology·2022· 28 citedOpen Access
Antigenic Sensitivity of Membrane-Proximal Targeting Chimeric Antigen Receptors can be Fine-Tuned through Hinge Truncation
2020· 3 citedOpen Access
A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells
Molecular Therapy — Methods & Clinical Development·2020· 107 citedOpen Access
Evaluation of recombinant adenovirus vectors and adjuvanted protein as a heterologous prime-boost strategy using HER2 as a model antigen
Vaccine·2019· 14 citedOpen Access
Development and characterization of a murine hepatoma model expressing hepatitis Cvirus (HCV) non-structural antigens for evaluating HCV vaccines
2018
Intrinsic Role of FoxO3a in the Development of CD8+ T Cell Memory
The Journal of Immunology·2013· 31 citedOpen Access
CD8+ T Cells Primed in the Periphery Provide Time-Bound Immune-Surveillance to the Central Nervous System
The Journal of Immunology·2011· 34 citedOpen Access
Backbone-methylated Analogues of the Principle Receptor Binding Region of Human Parathyroid Hormone
Journal of Biological Chemistry·2005· 16 citedOpen Access
Backbone-methylated analogues of the principal receptor binding region of human parathyroid hormone: Evidence for binding to both the N-terminal extracellular domain and extracellular loop region
NPARC·2005
The effects of parathyroid hormone fragments on bone formation and their lack of effects on the initiation of colon carcinogenesis in rats as indicated by preneoplastic aberrant crypt formation
Cancer Letters·2003· 6 cited
C-terminal fragment of parathyroid hormone-related protein, PTHrP-(107-111), stimulates membrane-associated protein kinase C activity and modulates the proliferation of human and murine skin keratinocytes
Journal of Cellular Physiology·1996· 39 cited
Parathyroid hormone fragments may stimulate bone growth in ovariectomized rats by activating adenylyl cyclase
Journal of Bone and Mineral Research·1994· 130 cited
Further definition of the protein kinase C activation domain of the parathyroid hormone
Journal of Bone and Mineral Research·1994· 128 cited
Parathyroid hormone fragments stimulate bone growth in ovariectomized rats by activating adenylyl cyclase
NPARC·1994
Protein kinase C-activating domains of parathyroid hormone-related protein
Journal of Bone and Mineral Research·1993· 49 citedOpen Access

Frequent Co-authors

Gordon E. Willick(7), Risini D. Weeratna(7), Rénald Gilbert(6), J. F. Whitfield(5), Tina Nguyen(5), Scott McComb(5), Christine Gadoury(4), Anne Marcil(4), Lyne Gagnon(3), Richard Isaacs(3), Balu Chakravarthy(3), Jon P. Durkin(3), Witold Neugebauer(3), Hervé Jouishomme(3), Darin Bloemberg(3), Ahmed Zafer(3), Komal Gurnani(3), Anindita Chattopadhyay(3), Robert A. Pon(3), Renu Dudani(3)