Ulrich Hübscher

University of Zurich — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

64h-index14.4kcitations266works0.02yr avg
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Research Topics

DNA Repair Mechanisms(154), DNA and Nucleic Acid Chemistry(59), Carcinogens and Genotoxicity Assessment(35), HIV/AIDS drug development and treatment(34), Bacterial Genetics and Biotechnology(33)

Publications266 total

A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres
International Journal of Molecular Sciences·2021· 3 citedOpen Access
Human Dna Polymerases: Biology, Medicine And Biotechnology
2017· 2 cited
Living on the Edge: DNA Polymerase Lambda between Genome Stability and Mutagenesis
Chemical Research in Toxicology·2017· 17 cited
Human DNA Polymerases
WORLD SCIENTIFIC eBooks·2017· 1 cited
Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity
Nucleic Acids Research·2016· 36 citedOpen Access
Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair
Nature Communications·2016· 38 citedOpen Access
DNA polymerases: Biology, diseases and biomedical applications
DNA repair·2015· 13 cited
Agnoprotein of polyomavirus BK interacts with proliferating cell nuclear antigen and inhibits DNA replication
Virology Journal·2015· 31 citedOpen Access
Expansion of CAG triplet repeats by human DNA polymerases λ and β in vitro, is regulated by flap endonuclease 1 and DNA ligase 1
DNA repair·2015· 12 cited
Gap-Directed Translesion DNA Synthesis of an Abasic Site on Circular DNA Templates by a Human Replication Complex
PLoS ONE·2014· 2 citedOpen Access
Specialized human DNA polymerases can incorporate ribonucleotides during lesion bypass and DNA repair (736.5)
The FASEB Journal·2014
Regulation of Human MutYH DNA Glycosylase by the E3 Ubiquitin Ligase Mule
Journal of Biological Chemistry·2014· 27 citedOpen Access
Faculty Opinions recommendation of Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2014
DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass
Proceedings of the National Academy of Sciences·2013· 45 citedOpen Access
Faculty Opinions recommendation of An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2013
Genotype–phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies
Free Radical Biology and Medicine·2013· 30 cited
Interplay of DNA polymerase lambda, Protection of Telomeres (Pot) 1 and TERRA in telomere elongation
The FASEB Journal·2013
The Human Tim-Tipin Complex Interacts Directly with DNA Polymerase ϵ and Stimulates Its Synthetic Activity
Journal of Biological Chemistry·2013· 20 citedOpen Access
Faculty Opinions recommendation of How a holoenzyme for DNA replication is formed.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2013
Mammalian Base Excision Repair: the Forgotten Archangel
Nucleic Acids Research·2013· 361 citedOpen Access
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Frequent Co-authors

Giovanni Maga(11), Silvio Spadari(11), Michael O. Hottiger(6), Vladimir N. Podust(6), Manuel Stucki(5), Kristijan Ramadan(5), Giuseppe Villani(5), Clive C. Kuenzle(5), Zophonı́as O. Jónsson(4), I. V. Shevelev(3), Elena Ferrari(3), Magali Toueille(3), Peter Gehrig(3), Paul O. Hassa(3), Romina Mossi(3), Stéphane Koundrioukoff(3), Max Gassmann(2), Pia Thömmes(2), Thomas Weiser(2), Juhani E. Syväoja(2)