Stéphane Koundrioukoff

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index2.2kcitations32works0.02yr avg
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Research Topics

DNA Repair Mechanisms(29), Cancer-related Molecular Pathways(9), Genomics and Chromatin Dynamics(8), Genetics and Neurodevelopmental Disorders(8), Epigenetics and DNA Methylation(7)

Publications32 total

ATR and TopBP1 oppose to control dormant origin building, providing a first defence against replication stress
2024Open Access
A post-irradiation-induced replication stress promotes RET proto-oncogene breakage
European Thyroid Journal·2024Open Access
The balance between ATR and DDK activities controls TopBP1-mediated locking of dormant origins at the pre-IC stage
2023· 6 citedOpen Access
<i>In vivo</i> reduction of <scp>RAD51</scp> ‐mediated homologous recombination triggers aging but impairs oncogenesis
The EMBO Journal·2023· 13 citedOpen Access
Firing of Replication Origins Is Disturbed by a CDK4/6 Inhibitor in a pRb-Independent Manner
International Journal of Molecular Sciences·2023· 2 citedOpen Access
Mistimed origin licensing and activation stabilize common fragile sites under tight DNA-replication checkpoint activation
Nature Structural & Molecular Biology·2023· 11 citedOpen Access
Palbociclib interferes with replication origin firing in a pRb independent manner
2022Open Access
<i>In vivo</i> inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis
2022· 1 citedOpen Access
The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin
Life·2021· 9 citedOpen Access
Unscheduled origin building in S-phase upon tight CDK1 inhibition suppresses CFS instability
2020· 3 citedOpen Access
Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide
Nature Communications·2019· 104 citedOpen Access
Transcription-mediated organization of the replication initiation program across large genes sets up common fragile sites genome-wide
2019Open Access
Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2
Molecular Cell·2018· 65 citedOpen Access
The impact of replication stress on replication dynamics and DNA damage in vertebrate cells
Nature Reviews Genetics·2017· 287 cited
PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1
Oncogene·2016· 48 cited
USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication
Molecular Oncology·2016· 46 citedOpen Access
Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage
Cell Reports·2016· 80 citedOpen Access
TIPIN depletion leads to apoptosis in breast cancer cells
Molecular Oncology·2015· 20 citedOpen Access
Updating the mechanisms of common fragile site instability: how to reconcile the different views?
Cellular and Molecular Life Sciences·2014· 59 citedOpen Access
The RBBP6/ZBTB38/MCM10 Axis Regulates DNA Replication and Common Fragile Site Stability
Cell Reports·2014· 70 citedOpen Access
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Frequent Co-authors

Michelle Debatisse(24), Olivier Brison(11), Anne-Marie Lachagès(6), Sami El Hilali(6), Chun-Long Chen(6), Dana Azar(5), Hervé Técher(4), Sandra Carignon(4), Ulrich Hübscher(4), Mélanie Schmidt(4), Yan Jaszczyszyn(4), Claude Thermes(4), Stefano Gnan(4), Su-Jung Kim(4), A Letessier(3), Raimundo Freire(3), Therese Wilhelm(3), Giuseppe Baldacci(3), Bernard S. López(3), Geneviève Almouzni(3)