Joseph Demeester

Ghent University — Belgium

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index7.6kcitations81works0.02yr avg
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Research Topics

RNA Interference and Gene Delivery(31), Advanced biosensing and bioanalysis techniques(23), Ultrasound and Hyperthermia Applications(11), Virus-based gene therapy research(9), Nanoparticle-Based Drug Delivery(8)

Publications81 total

Photodisruption of the Inner Limiting Membrane Promotes Retinal Engraftment of Stem-Cell Derived Retinal Ganglion Cells
Investigative Ophthalmology & Visual Science·2026Open Access
Disregarded Effect of Biological Fluids in siRNA Delivery: Human Ascites Fluid Severely Restricts Cellular Uptake of Nanoparticles
ACS Applied Materials & Interfaces·2015· 33 citedOpen Access
Coupling of drug containing liposomes to microbubbles improves ultrasound triggered drug delivery in mice
Journal of Controlled Release·2013· 66 cited
Targeted Liposome‐Loaded Microbubbles for Cell‐Specific Ultrasound‐Triggered Drug Delivery
Small·2013· 44 cited
Noncoding DNA in Lipofection of HeLa Cells—A Few Insights
Molecular Pharmaceutics·2013· 9 cited
Transport of Nanoparticles in Cystic Fibrosis Sputum and Bacterial Biofilms by Single-Particle Tracking Microscopy
Nanomedicine·2012· 118 cited
Efficient Transfection of Hepatocytes Mediated by mRNA Complexed to Galactosylated Cyclodextrins
Bioconjugate Chemistry·2012· 45 cited
The cytotoxic and immunogenic hurdles associated with non-viral mRNA-mediated reprogramming of human fibroblasts
Biomaterials·2012· 45 cited
Elucidating the Mechanisms Behind Sonoporation with Adeno-Associated Virus-Loaded Microbubbles
Molecular Pharmaceutics·2011· 44 citedOpen Access
Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier design
Journal of Controlled Release·2011· 203 cited
Activation of pluripotency-associated genes in mouse embryonic fibroblasts by non-viral transfection with in vitro-derived mRNAs encoding Oct4, Sox2, Klf4 and cMyc
Biomaterials·2011· 51 citedOpen Access
Nuclear Inclusion of Nontargeted and Chromatin-Targeted Polystyrene Beads and Plasmid DNA Containing Nanoparticles
Molecular Pharmaceutics·2011· 26 citedOpen Access
Self-assembled liposome-loaded microbubbles: The missing link for safe and efficient ultrasound triggered drug-delivery
Journal of Controlled Release·2011· 157 citedOpen Access
Adeno-associated virus loaded microbubbles as a tool for targeted gene delivery
Journal of Controlled Release·2010· 2 citedOpen Access
Ultrasound responsive doxorubicin-loaded microbubbles; towards an easy applicable drug delivery platform
Journal of Controlled Release·2010· 12 cited
Pulmonary delivery of mRNA: in vitro and in vivo evaluation
Drug Discovery Today·2010
siRNA containing nanoparticles: stability of encapsulation and particle size
Drug Discovery Today·2010
mRNA delivery to cervical carcinoma and mesenchymal stem cells mediated by cationic carriers
Drug Discovery Today·2010· 1 cited
mRNA transfection of cervical carcinoma and mesenchymal stem cells mediated by cationic carriers
Journal of Controlled Release·2010· 131 cited
The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls
Molecular Therapy·2009· 668 citedOpen Access
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Frequent Co-authors

Stefaan C. De Smedt(48), Niek N. Sanders(27), Roosmarijn E. Vandenbroucke(11), Kevin Braeckmans(9), Ine Lentacker(8), Joanna Rejman(6), Bruno G. De Geest(6), Koen Raemdonck(5), Bart Geers(5), Liesbeth Peeters(5), Barbara G. Stubbe(5), Elsa Van Rompaey(4), Kevin Buyens(4), Tom Meyvis(4), Geertrui Tavernier(3), Wim E. Hennink(3), Bart Lucas(3), Gleb B. Sukhorukov(2), Marc Leblans(2), Rudi Pauwels(2)