Cliff Rowe

Medicine · Health Sciences

19h-index3.0kcitations31works0.02yr avg
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Research Topics

Liver physiology and pathology(8), Ultrasound and Hyperthermia Applications(6), Pluripotent Stem Cells Research(5), Pancreatic function and diabetes(5), 3D Printing in Biomedical Research(5)

Publications30 total

Improved Therapeutic Delivery Targeting Clinically Relevant Orthotopic Human Pancreatic Tumors Engrafted in Immunocompromised Pigs Using Ultrasound-Induced Cavitation: A Pilot Study
Pharmaceutics·2023· 7 citedOpen Access
Detection, characterization, and spatial mapping of nucleated cavitation for drug delivery: From <i>in-vitro</i>-, through <i>in-vivo</i> to the clinic
The Journal of the Acoustical Society of America·2022· 1 cited
Ultrasound-induced cavitation and passive acoustic mapping: SonoTran platform performance and short-term safety in a large-animal model
Ultrasound in Medicine & Biology·2022· 14 cited
Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study
Toxicological Sciences·2018· 297 citedOpen Access
Ultrasound-mediated cavitation does not decrease the activity of small molecule, antibody or viral-based medicines
International Journal of Nanomedicine·2018· 15 citedOpen Access
Perfused human hepatocyte microtissues identify reactive metabolite-forming and mitochondria-perturbing hepatotoxins
Toxicology in Vitro·2017· 34 cited
Cavitation enhanced drug delivery <i> <i>in-vivo</i> </i> using combined B-mode guidance and real-time passive acoustic mapping: Challenges and results
The Journal of the Acoustical Society of America·2017· 2 cited
Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease
World Journal of Gastroenterology·2017· 140 citedOpen Access
Polymeric Cups for Cavitation-mediated Delivery of Oncolytic Vaccinia Virus
Molecular Therapy·2016· 56 citedOpen Access
Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile
Archives of Toxicology·2016· 135 citedOpen Access
Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome
Scientific Reports·2015· 38 citedOpen Access
Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney
Kidney International·2015· 52 citedOpen Access
Concise Review: Workshop Review: Understanding and Assessing the Risks of Stem Cell-Based Therapies
Stem Cells Translational Medicine·2015· 135 citedOpen Access
Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes
Journal of Hepatology·2014· 337 citedOpen Access
Proteomic analysis of primary colorectal cancer to generate response biomarkers for liver metastases.
Journal of Clinical Oncology·2014
Selecting the Right Drug Candidate
Genetic Engineering & Biotechnology News·2014· 1 cited
Phenotypic analysis of primary colorectal cancer to inform management of metastatic disease
The Lancet·2014
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
Archives of Toxicology·2013· 1.3k citedOpen Access
Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study
Cancer Chemotherapy and Pharmacology·2013· 25 cited
Proteome-Wide Analyses of Human Hepatocytes During Differentiation and Dedifferentiation
Hepatology·2013· 129 citedOpen Access
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Frequent Co-authors

Christopher E. Goldring(17), Neil R. Kitteringham(11), Roz Jenkins(6), Christian Coviello(6), B. Kevin Park(5), Rowena Sison‐Young(5), Neil A. Hanley(5), Rosalind E. Jenkins(5), Hassan Malik(4), Karen Piper Hanley(4), Robert Jones(4), M. Baxter(3), Andrew Berry(3), Stephen W. Fenwick(3), Kevin Park(3), James A. Heslop(3), Joanne Walsh(3), Rachel Myers(3), Calum Crake(3), Constantin Coussios(3)