Christopher E. Morgan

Case Western Reserve University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index887citations34works5.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(17), Antibiotic Resistance in Bacteria(7), RNA Research and Splicing(7), Bacteriophages and microbial interactions(7), Bacterial Genetics and Biotechnology(6)

Publications34 total

Mapping Protein–Protein Interactions at Birth: Single-Particle Cryo-EM Analysis of a Ribosome–Nascent Globin Complex
ACS Central Science·2024· 5 citedOpen Access
High-Resolution Structural Proteomics of Mitochondria Using the ‘Build and Retrieve’ Methodology
Molecular & Cellular Proteomics·2023· 7 citedOpen Access
Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms
ACS Chemical Biology·2023· 6 citedOpen Access
Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance
Microbiology Spectrum·2023· 17 citedOpen Access
Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome
PLoS Biology·2023· 29 citedOpen Access
Cryo-EM Structures of the Klebsiella pneumoniae AcrB Multidrug Efflux Pump
mBio·2023· 29 citedOpen Access
Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity
mBio·2023· 22 citedOpen Access
Toward structural-omics of the bovine retinal pigment epithelium
Cell Reports·2022· 15 citedOpen Access
A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes
Life Science Alliance·2022· 9 citedOpen Access
P26 Phenotypic and genotypic characterization of antimicrobial resistance in <i>Clostridioides difficile</i> in North Wales
JAC-Antimicrobial Resistance·2022Open Access
An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii
mBio·2022· 25 citedOpen Access
Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport
PLoS Biology·2021· 59 citedOpen Access
Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii
mBio·2021· 54 citedOpen Access
A. baumannii Ribosome-Eravacycline complex: Empty 70S
2021
A. baumannii Ribosome-Eravacycline complex: P-site tRNA 70S
2021
A. baumannii Ribosome-Eravacycline complex: 30S
2021
A. baumannii Ribosome-Eravacycline complex: 50S
2021
Cryo-EM as a tool to study bacterial efflux systems and the membrane proteome
Faculty Reviews·2021· 12 citedOpen Access
Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates
mBio·2021· 61 citedOpen Access
High-Resolution Insights into Nascent-Chain Conformation by Single-Particle Cryo-Electron Microscopy
Biophysical Journal·2021Open Access
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Frequent Co-authors

Edward Yu(25), Zhemin Zhang(8), Chih‐Chia Su(7), Blanton S. Tolbert(6), Robert A. Bonomo(5), Meinan Lyu(4), Philip A. Klenotic(3), Meng Cui(3), Jani Reddy Bolla(2), Carol V. Robinson(2), Wei Huang(2), Derek J. Taylor(2), Michele Tolbert(2), Mei-Ling Li(2), Niyati Jain(2), James E. Kirby(2), Masaru Miyagi(2), Marcin Golczak(2), Meranda M. Masse(2), Silvia Cavagnero(2)