Nicole L. van der Weerden

La Trobe University — Australia

Immunology and Microbiology · Life Sciences

21h-index2.3kcitations31works16.02yr avg
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Research Topics

Antimicrobial Peptides and Activities(25), Biochemical and Structural Characterization(22), Transgenic Plants and Applications(6), Plant-Microbe Interactions and Immunity(4), Protein Hydrolysis and Bioactive Peptides(4)

Publications31 total

Hyperpolarisation of Mitochondrial Membranes Is a Critical Component of the Antifungal Mechanism of the Plant Defensin, Ppdef1
Journal of Fungi·2024· 16 citedOpen Access
The Plant Defensin Ppdef1 Is a Novel Topical Treatment for Onychomycosis
Journal of Fungi·2023· 9 citedOpen Access
Membrane binding properties of plant defensins
Phytochemistry·2023· 9 cited
32994 Pezadeftide is a potent antifungal peptide with rapid fungicidial activity via a unique mechanism of action
Journal of the American Academy of Dermatology·2022· 2 cited
Improving the Digestibility of Plant Defensins to Meet Regulatory Requirements for Transgene Products in Crop Protection
Frontiers in Plant Science·2020· 9 citedOpen Access
Screening the <i>Saccharomyces cerevisiae</i> Nonessential Gene Deletion Library Reveals Diverse Mechanisms of Action for Antifungal Plant Defensins
Antimicrobial Agents and Chemotherapy·2019· 9 citedOpen Access
A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein
Scientific Reports·2019· 60 citedOpen Access
The interaction with fungal cell wall polysaccharides determines the salt tolerance of antifungal plant defensins
The Cell Surface·2019· 26 citedOpen Access
Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32
Frontiers in Microbiology·2019· 71 citedOpen Access
3 / The plant defensin HXP124 has the potential to be a new safe and effective topical treatment for onychomycosis
2018· 2 cited
The evolution, function and mechanisms of action for plant defensins
Seminars in Cell and Developmental Biology·2018· 223 citedOpen Access
Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta
Journal of Experimental Botany·2017· 63 citedOpen Access
Synergistic Activity between Two Antifungal Proteins, the Plant Defensin NaD1 and the Bovine Pancreatic Trypsin Inhibitor
mSphere·2017· 17 citedOpen Access
Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant
Antimicrobial Agents and Chemotherapy·2016· 46 citedOpen Access
The plant defensin NaD1 introduces membrane disorder through a specific interaction with the lipid, phosphatidylinositol 4,5 bisphosphate
Biochimica et Biophysica Acta (BBA) - Biomembranes·2016· 50 citedOpen Access
Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase
Nature Communications·2015· 256 citedOpen Access
Bovine pancreatic trypsin inhibitor is a new antifungal peptide that inhibits cellular magnesium uptake
Molecular Microbiology·2014· 26 citedOpen Access
Phosphoinositide-mediated oligomerization of a defensin induces cell lysis
eLife·2014· 186 citedOpen Access
Agp2p, the Plasma Membrane Transregulator of Polyamine Uptake, Regulates the Antifungal Activities of the Plant Defensin NaD1 and Other Cationic Peptides
Antimicrobial Agents and Chemotherapy·2014· 29 citedOpen Access
Author response: Phosphoinositide-mediated oligomerization of a defensin induces cell lysis
2014· 3 citedOpen Access
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Frequent Co-authors

Marilyn A. Anderson(27), Mark R. Bleackley(16), David J. Craik(9), Kathy Parisi(8), Brigitte M. E. Hayes(7), Pedro Quimbar(6), Mark D. Hulett(6), Thomas Shafee(5), Fung T. Lay(5), Ivan K. H. Poon(5), Jennifer A. E. Payne(5), Karen S. Harris(4), Thomas Durek(4), Prem K. Veneer(4), James A. McKenna(4), Simon Poon(4), Edward K. Gilding(3), Amy A. Baxter(3), Grant Mills(3), Thanh Kha Phan(3)