Michael J. Gait

MRC Laboratory of Molecular Biology — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

68h-index14.8kcitations297works0.32yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(136), Advanced biosensing and bioanalysis techniques(124), RNA Interference and Gene Delivery(106), RNA and protein synthesis mechanisms(71), RNA Research and Splicing(37)

Publications297 total

Author response for "Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in <i>BTK</i>/<i>Tec</i> double deficient X-linked agammaglobulinemia model"
2025
Author response for "Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in <i>BTK</i>/<i>Tec</i> double deficient X-linked agammaglobulinemia model"
2025
Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in <i>BTK</i> / <i>Tec</i> double deficient X-linked agammaglobulinemia model
RSC Chemical Biology·2025· 1 citedOpen Access
Modulation of Pro-Inflammatory IL-6 Trans-Signaling Axis by Splice Switching Oligonucleotides as a Therapeutic Modality in Inflammation
Cells·2023· 5 citedOpen Access
Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy
JCI Insight·2022· 55 citedOpen Access
Synthesis of Nucleic Acids
2022· 4 cited
Introduction and Overview
2022Open Access
Glossary
2022Open Access
Introduction and History of the Chemistry of Nucleic Acids Therapeutics
Methods in molecular biology·2022· 15 citedOpen Access
Dystrophin involvement in peripheral circadian SRF signalling
Life Science Alliance·2021· 7 citedOpen Access
Systemic antibody-oligonucleotide delivery to the central nervous system ameliorates mouse models of spinal muscular atrophy
2021· 9 citedOpen Access
Dystrophin regulates peripheral circadian SRF signalling
2021Open Access
Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides
Nucleic Acid Therapeutics·2021· 14 citedOpen Access
Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice
Journal of Clinical Investigation·2019· 100 citedOpen Access
Advances in Nucleic Acid Therapeutics
2019· 34 cited
History and Development of Nucleotide Analogues in Nucleic Acids Drugs
2019· 11 cited
Evaluation of Cell-Penetrating Peptide Delivery of Antisense Oligonucleotides for Therapeutic Efficacy in Spinal Muscular Atrophy
Methods in molecular biology·2019· 10 cited
Daniel McGillivray Brown. 3 February 1923—24 April 2012
Biographical Memoirs of Fellows of the Royal Society·2018
Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment
Nucleic Acid Therapeutics·2018· 79 citedOpen Access
Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment
Human Molecular Genetics·2018· 13 citedOpen Access
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Frequent Co-authors

Andrey Arzumanov(11), Jonathan Karn(10), Matthew J. A. Wood(10), Bernard Lebleu(7), Martin M. Fabani(5), Corinne Betts(5), Suzan M. Hammond(5), Amer F. Saleh(5), Mahavir Singh(4), Caroline Godfrey(4), Samir EL Andaloussi(4), Donna Williams(4), Adrián Gabriel Torres(4), Rachida Abes(4), Mohinder Singh(4), Gabriela D. Ivanova(4), Saïd Abes(4), Shaun Heaphy(3), Simon W. Jones(3), Liz O’Donovan(3)