Andrey Arzumanov

University of Oxford — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index2.7kcitations74works0.02yr avg
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Research Topics

RNA Interference and Gene Delivery(39), DNA and Nucleic Acid Chemistry(36), Advanced biosensing and bioanalysis techniques(31), HIV/AIDS drug development and treatment(18), Biochemical and Molecular Research(12)

Publications74 total

Peptide-conjugated antimiRs improve myotonic dystrophy type 1 phenotypes by promoting endogenous MBNL1 expression
Molecular Therapy — Nucleic Acids·2023· 13 citedOpen Access
Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides
Nucleic Acid Therapeutics·2021· 14 citedOpen Access
Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice
Journal of Clinical Investigation·2019· 100 citedOpen Access
Systemic Delivery of Peptide-Conjugated Antisense Oligonucleotides Leads to Long-Lasting Correction of Myotonic Dystrophy Type I
HAL (Le Centre pour la Communication Scientifique Directe)·2019
Low-dose of peptide-conjugate antisense oligonucleotides targeting CUGexp-RNA in murine skeletal muscles normalizes Myotonic Dystrophy 1 phenotype
HAL (Le Centre pour la Communication Scientifique Directe)·2019
Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment
Nucleic Acid Therapeutics·2018· 79 citedOpen Access
PPMO's as Therapeutic Modulators for Myotonic Dystrophy Type 1
Oxford University Research Archive (ORA) (University of Oxford)·2018Open Access
Enhanced systemic delivery of antisense oligonucleotides using cell-penetrating peptide to reverse RNA toxicity in DM1
HAL (Le Centre pour la Communication Scientifique Directe)·2017
Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides
Nucleic Acid Therapeutics·2015· 20 citedOpen Access
Parallel Synthesis of Cell-Penetrating Peptide Conjugates of PMO Toward Exon Skipping Enhancement in Duchenne Muscular Dystrophy
Nucleic Acid Therapeutics·2014· 20 citedOpen Access
Enhanced splice correction by 3′, 5′-serinol and 2′-(ω-<i>O</i>-methylserinol) guarded OMe-RNA/DNA mixmers in cells
Artificial DNA PNA & XNA·2013· 3 citedOpen Access
Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo
Organic & Biomolecular Chemistry·2013· 21 citedOpen Access
Overview of Alternative Oligonucleotide Chemistries for Exon Skipping
Methods in molecular biology·2012· 42 cited
Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment
Molecular Therapy — Nucleic Acids·2012· 220 citedOpen Access
Pip5 Transduction Peptides Direct High Efficiency Oligonucleotide-mediated Dystrophin Exon Skipping in Heart and Phenotypic Correction in mdx Mice
Molecular Therapy·2011· 133 citedOpen Access
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation
Nucleic Acids Research·2011· 228 citedOpen Access
Enhancement of exon skipping and dystrophin production by 3'-peptide conjugates of morpholino (PMO) oligonucleotides in a mdx mouse model of Duchenne muscular dystrophy
2011· 4 cited
Novel cell penetrating peptides for skeletal and cardiac muscle delivery of PMO antisense oligonucleotides for the treatment of duchenne muscular dystrophy.
View·2011
Splice Redirection as a Convenient Assay to Monitor CPP–ON Efficiency and Mechanism
Methods in molecular biology·2010· 3 cited
Synthesis and Splice-Redirecting Activity of Branched, Arginine-Rich Peptide Dendrimer Conjugates of Peptide Nucleic Acid Oligonucleotides
Bioconjugate Chemistry·2010· 50 citedOpen Access
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Frequent Co-authors

Michael J. Gait(38), Matthew J. A. Wood(11), Bernard Lebleu(10), Gabriela D. Ivanova(8), Rachida Abes(8), Jean‐Jacques Toulmé(7), Alexander A. Krayevsky(7), Suzan M. Hammond(6), Amer F. Saleh(6), Saïd Abes(6), John J. Turner(5), Gabriela Ivanova(5), Natalia Dyatkina(5), Corinne Betts(4), HaiFang Yin(4), Donna Williams(4), Jesper Wengel(4), Dmitry A. Stetsenko(4), Lyubov S. Victorova(4), Sandrine Reigadas(4)