Gen Wen

Hebei General Hospital — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index1.7kcitations39works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(11), Cellular transport and secretion(10), Hormonal Regulation and Hypertension(6), Retinoids in leukemia and cellular processes(4), Biotin and Related Studies(4)

Publications39 total

Machine Learning-Driven Evaluation of Lipid Markers for Cardiovascular Risk in Chronic Kidney Disease Patients: An Analysis from NHANES
2025Open Access
Heritable Influence of DBH on Adrenergic and Renal Function: Twin and Disease Studies
PLoS ONE·2013· 12 citedOpen Access
Heredity and cardiometabolic risk
Journal of Hypertension·2012· 10 citedOpen Access
Expression and functional role of vacuolar H+-ATPase in human hepatocellular carcinoma
Carcinogenesis·2012· 71 cited
Genetic Variation Within a Metabolic Motif in the Chromogranin A Promoter: Pleiotropic Influence on Cardiometabolic Risk Traits in Twins
American Journal of Hypertension·2011· 7 citedOpen Access
Adiposity, insulin indices, and adipokine profile through the pubertal transition in overweight latina adolescents with and without polycystic ovarian syndrome (PCOS)
Fertility and Sterility·2011Open Access
Proteomic Analysis Yields an Unexpected <i>Trans</i> -Acting Point in Control of the Human Sympathochromaffin Phenotype
Circulation Cardiovascular Genetics·2011· 2 citedOpen Access
Catecholamine Storage Vesicles: Role of Core Protein Genetic Polymorphisms in Hypertension
Current Hypertension Reports·2010· 20 citedOpen Access
Naturally Occurring Genetic Variants in Human Chromogranin A (CHGA) Associated with Hypertension as well as Hypertensive Renal Disease
Cellular and Molecular Neurobiology·2010· 10 citedOpen Access
Human Dopamine  -Hydroxylase Promoter Variant Alters Transcription in Chromaffin Cells, Enzyme Secretion, and Blood Pressure
American Journal of Hypertension·2010· 20 citedOpen Access
Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/experimental approach
Mammalian Genome·2010· 8 citedOpen Access
Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure
Journal of Hypertension·2009· 57 citedOpen Access
Peptide YY (PYY) Gene Polymorphisms in the 3′-Untranslated and Proximal Promoter Regions Regulate Cellular Gene Expression and PYY Secretion and Metabolic Syndrome Traits<i>in Vivo</i>
The Journal of Clinical Endocrinology & Metabolism·2009· 18 citedOpen Access
Adrenergic Polymorphism and the Human Stress Response
Annals of the New York Academy of Sciences·2008· 21 citedOpen Access
Increased susceptibility of human small airway epithelial cells to apoptosis after long term arsenate treatment
The Science of The Total Environment·2008· 2 citedOpen Access
Naturally Occurring Human Genetic Variation in the 3′-Untranslated Region of the Secretory Protein Chromogranin A Is Associated With Autonomic Blood Pressure Regulation and Hypertension in a Sex-Dependent Fashion
Journal of the American College of Cardiology·2008· 44 citedOpen Access
Common genetic variants in the chromogranin A promoter alter autonomic activity and blood pressure
Kidney International·2008· 30 citedOpen Access
Chromogranin A Polymorphisms Are Associated With Hypertensive Renal Disease
Journal of the American Society of Nephrology·2008· 63 citedOpen Access
Spectral study on the interaction of cryptophane-A and neutral molecules CHnCl4 − n (n=0, 1, 2)
Talanta·2007· 12 cited
Biogenesis of the Secretory Granule:  Chromogranin A Coiled-Coil Structure Results in Unusual Physical Properties and Suggests a Mechanism for Granule Core Condensation
Biochemistry·2007· 40 cited
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Frequent Co-authors

Daniel T. O’Connor(27), Fangwen Rao(20), Bruce A. Hamilton(20), Manjula Mahata(17), Nicholas J. Schork(17), Sushil K. Mahata(17), Michael G. Ziegler(15), Kuixing Zhang(11), Rany M. Salem(10), Laurent Taupenot(10), Brinda K. Rana(9), Madhusudan Das(7), Sushil K. Mahata(7), Peter E. Cadman(7), Juan L. Rodríguez-Flores(7), Sucheta M. Vaingankar(6), Mats Stridsberg(6), Yuqing Chen(6), Maple M. Fung(6), Ryan S. Friese(6)