Bruce A. Hamilton

UC San Diego Health System — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index5.3kcitations102works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(14), Cellular transport and secretion(12), CRISPR and Genetic Engineering(10), Epigenetics and DNA Methylation(8), Chromosomal and Genetic Variations(8)

Publications102 total

Tulp3 quantitative alleles titrate requirements for viability, brain development, and kidney homeostasis but do not suppress Zfp423 mutations in mice
PLoS Genetics·2025Open Access
Nonequivalence of <i>Zfp423</i> premature termination codons in mice
Genetics·2025Open Access
Nonequivalence of <i>Zfp423</i> premature termination codons in mice
2025Open Access
<i>Tulp3</i> quantitative alleles titrate requirements for viability, brain development, and kidney homeostasis but do not suppress <i>Zfp423</i> mutations in mice
2025Open Access
<i>Ankfn1</i> -mutant vestibular defects require loss of both ancestral and derived paralogs for penetrance in zebrafish
G3 Genes Genomes Genetics·2021· 2 citedOpen Access
<i>Ankfn1</i> vestibular defects in zebrafish require mutations in both ancestral and derived paralogs
2021Open Access
Mice Lacking Phosphatidylinositol Transfer Protein-α Exhibit Spinocerebellar Degeneration, Intestinal and Hepatic Steatosis, and Hypoglycemia
UNC Libraries·2021Open Access
Inducible Yeast Two-Hybrid with Quantitative Measures
2021· 1 citedOpen Access
Strain-Dependent Modifier Genes Determine Survival in <i>Zfp423</i> Mice
G3 Genes Genomes Genetics·2020· 2 citedOpen Access
ZNF423 patient variants, truncations, and in-frame deletions in mice define an allele-dependent range of midline brain abnormalities
PLoS Genetics·2020· 13 citedOpen Access
Strain-dependent modifier genes determine survival in <i>Zfp423</i> mice
2020· 1 citedOpen Access
<i>ZNF423</i> patient variants, truncations, and in-frame deletions in mice define an allele-dependent range of midline brain abnormalities
2020· 3 citedOpen Access
ZNF423 orthologs are highly constrained in vertebrates but show domain-level plasticity across invertebrate lineages
2020· 8 citedOpen Access
The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina
Aging Cell·2020· 100 citedOpen Access
The Lipid Elongation Enzyme ELOVL2 is a molecular regulator of aging in the retina
2019· 10 citedOpen Access
TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis
Developmental Biology·2018· 25 citedOpen Access
Regeneration of fat cells from myofibroblasts during wound healing
Science·2017· 556 citedOpen Access
Deep Reads: Favorites from a Few Different Shelves
PLoS Genetics·2016Open Access
Identification of novel loci affecting circulating chromogranins and related peptides
Human Molecular Genetics·2016· 17 citedOpen Access
Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6C low Monocytes while Preserving Macrophage Gene Function
Immunity·2016· 163 citedOpen Access
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Frequent Co-authors

Daniel T. O’Connor(17), Gen Wen(16), Manjula Mahata(14), Fangwen Rao(13), Nicholas J. Schork(10), Sushil K. Mahata(10), Michael G. Ziegler(9), Rany M. Salem(6), Mats Stridsberg(6), Kuixing Zhang(5), Juan L. Rodríguez-Flores(5), Maple M. Fung(5), Eric S. Lander(4), Michael Palazzolo(4), David Gold(4), Madhusudan Das(4), Sucheta M. Vaingankar(4), Brinda K. Rana(4), Sushil K. Mahata(4), Nitish R. Mahapatra(4)