Ko‐Chung Lin

Medicine · Health Sciences

12h-index882citations13works0.02yr avg
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Research Topics

Cell Adhesion Molecules Research(5), Asthma and respiratory diseases(2), Hepatitis C virus research(2), Carbohydrate Chemistry and Synthesis(2), Monoclonal and Polyclonal Antibodies Research(2)

Publications13 total

Novel long‐acting ropeginterferon alfa‐2b: Pharmacokinetics, pharmacodynamics and safety in a phase I clinical trial
British Journal of Clinical Pharmacology·2021· 29 citedOpen Access
The preeminence of clusters
Bioentrepreneur·2007· 1 citedOpen Access
Tricyclic Imidazoline Derivatives as Potent and Selective Adenosine A<sub>1</sub>Receptor Antagonists
Journal of Medicinal Chemistry·2006· 14 citedOpen Access
N-Terminally PEGylated Human Interferon-β-1a with Improved Pharmacokinetic Properties and in Vivo Efficacy in a Melanoma Angiogenesis Model
Bioconjugate Chemistry·2005· 144 cited
A Small Molecule Very Late Antigen–4 Antagonist Can Inhibit Ovalbumin-induced Lung Inflammation
American Journal of Respiratory and Critical Care Medicine·2003· 44 cited
3D QSAR (COMFA) of a series of potent and highly selective VLA-4 antagonists
Journal of Computer-Aided Molecular Design·2002· 15 cited
A Small-Molecule, Tight-binding Inhibitor of the Integrin α <sub>4</sub> β <sub>1</sub> Blocks Antigen-induced Airway Responses and Inflammation in Experimental Asthma in Sheep
American Journal of Respiratory and Critical Care Medicine·2000· 86 cited
Selective, Tight-Binding Inhibitors of Integrin α4β1 That Inhibit Allergic Airway Responses
Journal of Medicinal Chemistry·1999· 207 citedOpen Access
Identification of Ligand Binding Sites on Integrin α4β1 through Chemical Cross-Linking
Biochemistry·1998· 29 cited
Very late antigen 4 (VLA4) antagonists as anti-inflammatory agents
Current Opinion in Chemical Biology·1998· 95 cited
EPSP synthase inhibitor design II. The importance of the 3-phosphate group for ligand binding at the shikimate-3-phosphate site &amp; the identification of 3-malonate ethers as novel 3-phosphate mimics.
Bioorganic & Medicinal Chemistry Letters·1993· 15 cited
EPSP Synthase: The Design and Synthesis of Bisubstrate Inhibitors Incorporating Novel 3-Phosphate Mimics
Phosphorus, sulfur, and silicon and the related elements·1993· 130 cited
The intramolecular cycloaddition of azides with ω-chloroalkenes. A facile route to (±)-swainsonine and other indolizidine alkaloids
Tetrahedron Letters·1990· 73 citedOpen Access

Frequent Co-authors

R. Blake Pepinsky(4), Steven P. Adams(4), Roy R. Lobb(3), Humayun S. Ateeq(2), Craig Zimmerman(2), Alfredo Castro(2), Wen‐Cherng Lee(2), Charles E. Hammond(2), Diane R. Leone(2), William M. Abraham(2), Russell C. Petter(2), Ling Ling Chen(2), Liqing Chen(2), Alan Gill(2), James A. Sikorski(2), Michael J. Miller(2), Diane S. Braccolino(2), Darryl G. Cleary(2), Kenneth J. Gruys(2), Chao Han(2)