Naomi L. Esmon

Oklahoma Medical Research Foundation — United States

Medicine · Health Sciences

29h-index5.6kcitations53works0.02yr avg
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Research Topics

Blood Coagulation and Thrombosis Mechanisms(37), Venous Thromboembolism Diagnosis and Management(9), Venomous Animal Envenomation and Studies(8), Coagulation, Bradykinin, Polyphosphates, and Angioedema(8), Vitamin K Research Studies(8)

Publications53 total

Safety and efficacy of an anti–human APC antibody for prophylaxis of congenital factor deficiencies in preclinical models
Blood·2023· 14 citedOpen Access
Blocking human protein C anticoagulant activity improves clotting defects of hemophilia mice expressing human protein C
Blood Advances·2022· 14 citedOpen Access
EPCR Signaling Controls the Activity of Hematopoietic Stem Cells Independent of Coagulation Regulation
Blood·2021· 2 cited
Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice
Blood·2016· 11 citedOpen Access
Neutrophil Extracellular Traps Drive Bleomycin‐Induced Lung Fibrosis by Regulating TGFβ1‐Dependent Interactions of Platelets and Macrophages
The FASEB Journal·2016· 7 cited
Comparison of Methods to Determine Rivaroxaban anti-factor Xa activity
Thrombosis Research·2014· 47 cited
Inhibition of Endogenous Activated Protein C Attenuates Experimental Autoimmune Encephalomyelitis by Inducing Myeloid-Derived Suppressor Cells
The Journal of Immunology·2013· 31 citedOpen Access
expressing the anticoagulant prothrombin mutant W215A/E217A The development of inflammatory joint disease is attenuated in mice
2012
Extracellular Histones Are Mediators of Death through TLR2 and TLR4 in Mouse Fatal Liver Injury
The Journal of Immunology·2011· 517 citedOpen Access
Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4
Blood·2011· 820 citedOpen Access
The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A
Blood·2011· 38 citedOpen Access
The Link Between Vascular Features and Thrombosis
Annual Review of Physiology·2011· 90 cited
The Endothelial Protein C Receptor Supports Tissue Factor Ternary Coagulation Initiation Complex Signaling through Protease-activated Receptors
Journal of Biological Chemistry·2010· 94 citedOpen Access
The Endothelial Protein C Receptor Supports TF-VIIa-Xa Ternary Complex Signaling through Protease-Activated Receptors.
Blood·2010
Regulation of Complement Activation by Thrombomodulin.
Blood·2009· 4 cited
Extracellular histones are major mediators of death in sepsis
Nature Medicine·2009· 1.5k citedOpen Access
Thrombomodulin Mutations in Atypical Hemolytic–Uremic Syndrome
New England Journal of Medicine·2009· 542 citedOpen Access
CD73-generated Adenosine Regulates Thrombomodulin Expression (94.29)
The Journal of Immunology·2009
Function of Beta2-GPI in Inhibiting the Oxidized Phospholipids Dependent APC Activity by Antiphospholipid IgG from APS Patients.
Blood·2006
Effects of membrane and soluble EPCR on the hemostatic balance and endotoxemia in mice
Blood·2006· 26 citedOpen Access
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Frequent Co-authors

Charles T. Esmon(38), Omid Safa(8), Jun Xu(7), Mikhail D. Smirnov(7), Gary Ferrell(6), Charles Esmon(6), Jian-Ming Gu(5), Dongfeng Qu(4), Deborah J. Stearns-Kurosawa(3), Xunzhen Zheng(3), Arthur E. Johnson(3), Marc Monestier(2), Concetta T. Ammollo(2), Fabrizio Semeraro(2), Fletcher B. Taylor(2), James H. Morrissey(2), Mieke Delvaeye(2), Edward M. Conway(2), Zolton Laszik(2), Shinichiro Kurosawa(2)