Richard A. Rippe

University of North Carolina at Chapel Hill — United States

Medicine · Health Sciences

47h-index7.9kcitations118works0.02yr avg
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Research Topics

Liver physiology and pathology(66), Liver Disease Diagnosis and Treatment(39), TGF-β signaling in diseases(12), Liver Disease and Transplantation(9), Cell Adhesion Molecules Research(8)

Publications118 total

Peroxisome Proliferator-activated Receptor γ Induces a Phenotypic Switch from Activated to Quiescent Hepatic Stellate Cells
UNC Libraries·2021Open Access
Interleukin-6 Increases Rat Metalloproteinase-13 Gene Expression through Stimulation of Activator Protein 1 Transcription Factor in Cultured Fibroblasts
UNC Libraries·2021Open Access
Anti-Fas Induces Hepatic Chemokines and Promotes Inflammation by an NF-κB-independent, Caspase-3-dependent Pathway
UNC Libraries·2021Open Access
Expression of Interleukin-10 by in Vitro and in Vivo Activated Hepatic Stellate Cells
UNC Libraries·2021Open Access
Role of AP-1 in the Coordinate Induction of Rat Glutamate-cysteine Ligase and Glutathione Synthetase by tert -Butylhydroquinone
UNC Libraries·2021· 4 citedOpen Access
The Role of Focal Adhesion Kinase-Phosphatidylinositol 3-Kinase-Akt Signaling in Hepatic Stellate Cell Proliferation and Type I Collagen Expression
UNC Libraries·2021Open Access
SMAD and p38 MAPK Signaling Pathways Independently Regulate α1(I) Collagen Gene Expression in Unstimulated and Transforming Growth Factor-β-stimulated Hepatic Stellate Cells
UNC Libraries·2021· 1 citedOpen Access
Peroxisome Proliferator-activated Receptor γ Suppresses Proximal α1(I) Collagen Promoter via Inhibition of p300-facilitated NF-I Binding to DNA in Hepatic Stellate Cells
UNC Libraries·2021Open Access
The Role of p70 S6K in Hepatic Stellate Cell Collagen Gene Expression and Cell Proliferation
UNC Libraries·2021Open Access
Binding of Upstream Stimulatory Factor to an E-box in the 3′-Flanking Region Stimulates α1(I) Collagen Gene Transcription
UNC Libraries·2021Open Access
Src kinase participates in LPS-induced activation of NADPH oxidase
UNC Libraries·2021Open Access
Mutation of the 5′-Untranslated Region Stem-Loop Structure Inhibits α1(I) Collagen Expression in Vivo
UNC Libraries·2020Open Access
Distinct Populations of Hepatic Stellate Cells in the Mouse Liver Have Different Capacities for Retinoid and Lipid Storage
UNC Libraries·2020Open Access
Inhibition of transforming growth factor-β/Smad signaling improves regeneration of small-for-size rat liver grafts
UNC Libraries·2020Open Access
The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation
UNC Libraries·2020· 4 citedOpen Access
Inhibition of phosphatidylinositol 3-kinase signaling in hepatic stellate cells blocks the progression of hepatic fibrosis
UNC Libraries·2020· 6 citedOpen Access
Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis
UNC Libraries·2020Open Access
Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species
UNC Libraries·2020Open Access
Accumulation of Hedgehog-Responsive Progenitors Parallels Alcoholic Liver Disease Severity in Mice and Humans
UNC Libraries·2020Open Access
TNFα is required for cholestasis-induced liver fibrosis in the mouse
UNC Libraries·2020Open Access
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Frequent Co-authors

David A. Brenner(26), Laura W. Schrum(9), Hidekazu Tsukamoto(9), Liu Yang(6), Erwin Gäbele(5), Michael Breindl(5), Ramón Bataller(5), Christopher J. Parsons(4), Ian N. Hines(4), Shigang Xiong(3), Shigeki Tsukada(3), Shimon Reif(3), Alon Lang(3), Yutaka Yata(3), J. Marc Rhoads(3), Robert A. Argenzio(3), John Westwick(3), Andrea Gillan(3), Terry Morris(3), Robert Schoonhoven(3)